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Term Description

This term is used for the detection of nuclear Epstein-Barr virus-encoded RNA 1 (EBER1) by in situ hybridization on tissue. Presence of EBER1 indicates a latent EBV infection.
EBV encodes two small nuclear RNAs, EBER1 and EBER2, which are the most abundant viral transcripts in latently infected cells. They are non-polyadenylated and thus not translated into protein. Their function is to inhibit interferon-mediated antiviral effects and apoptosis. Since they are expressed at high levels (around a million copies per latently infected cell), they are considered to be an ideal marker of latent EBV infection. In situ hybridization targeting one or both EBERs is used to determine whether a biopsied tumor is EBV-related.

The Epstein-Barr virus (EBV), also called Human herpesvirus 4 (HHV-4), is a virus of the herpes family (which includes Herpes simplex virus and Cytomegalovirus). It is one of the most common viruses in humans. Individuals infected with EBV are often asymptomatic but EBV commonly causes infectious mononucleosis. It is named after Michael Epstein and Yvonne Barr, who together with Bert Achong discovered the virus in 1964.
Source: Wikipedia

LOINC Names Get Info

Fully-Specified Name
Epstein-Barr virus-encoded RNA 1:PrThr:Pt:Tiss:Ord:Probe
Long Common Name
Epstein-Barr virus-encoded RNA 1 [Presence] in Tissue by Probe
Short Name
EBV-encoded RNA1 Tiss Ql Probe
Display Name
EBV-encoded RNA 1 Probe Ql (Tiss)
Consumer Name Alpha Get Info
Epstein Barr virus (EBV)-encoded RNA 1, Tissue

Part Model Get Info

  • Component
    Epstein-Barr virus-encoded RNA 1
    LP135458-0
    • Analyte
      Epstein-Barr virus-encoded RNA 1
      LP135458-0
      • Component Numerator
        Epstein-Barr virus-encoded RNA 1
        LP135458-0
        • Component Numerator Core
          Epstein-Barr virus-encoded RNA 1
          LP135458-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Tiss
    LP7641-6
    • System Core
      Tiss
      LP7641-6
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Probe
    LP6459-4

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.63 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus Epsteina-Barrové-kódovaná RNA 1:Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Sonda
el-GRGreek (Greece)RNA 1 κωδικοποιημένο από τον ιό Epstein-Barr:PrThr:Pt:Ιστός:Ord:Ανιχνευτής
Synonyms: MICRO Ord PrThr Pt RNA RNA 1 κωδικοποιημένο από τον ιό Epstein-Barr Ανιχνευτής Ιός Ιός Epstein Barr Ιστός
es-ESSpanish (Spain)Virus Epstein-Barrs.ARN 1 codificado:PrThr:Punto temporal:Tejido:Ord:Sonda de DNA
es-MXSpanish (Mexico)ARN 1 codificado por el virus de Epstein-Barr:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Investigacion
fr-FRFrench (France)Epstein barr virus 1 ARN encodé:Présence/Seuil:Ponctuel:Tissu:Qualitatif:PCR
it-ITItalian (Italy)Epstein-Barr virus, RNA 1 codificato:PrThr:Pt:Tessuto:Ord:Sonda
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) RNA 1 codificato di Epstein-Barr virus Sonda di DNA Tessuto & Strisci Virus di Epstein Barr
nl-NLDutch (Netherlands)Epstein-Barr-virus-encoded RNA 1:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:DNA-sonde
pl-PLPolish (Poland)Epstein-Barr wirus-produkowane RNA 1:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:sonda
Synonyms: RNA 1 kodowane przez wirusa EBV Wirus Epsteina-Barr
ru-RURussian (Russian Federation)Эпштейн-Барр вирусом кодированная РНК 1:PrThr:ТчкВрм:Тк:Пор:Проба
Synonyms: ДНК проба;ДНК зонд Порядковый Ткань и мазки Точка во времени;Момент
tr-TRTurkish (Turkey)Epstein-Barr virus-encoded RNA 1:MevcEşik:Zmlı:Doku:Srl:Prob
Synonyms: Mevcut
zh-CNChinese (China)Epstein Barr 病毒编码型 RNA 1:存在情况或阈值:时间点:组织与涂片:序数型:DNA探针
Synonyms: Ⅰ Burkitt 淋巴瘤;EB 病毒;EBV;人类疱疹病毒 4 型;人类疱疹病毒 IV 型;人类疱疹病毒第四型;传染性单核细胞增多症;胃癌;鼻咽癌;爱波斯坦-巴尔病毒;埃波斯坦-巴尔病毒;E.B.病毒;埃-巴二氏病毒;疱疹病毒;传染性单核细胞增多症;癌症 Epstein Barr 病毒编码的 RNA 1;EB 病毒编码型 RNA 1;EBV 编码型 RNA 1;人类疱疹病毒 4 型编码型 RNA 1;人类疱疹病毒 IV 型编码型 RNA 1 I 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 核糖核酸;Ribonucleic acid 爱波斯坦 爱泼斯坦 脱氧核糖核酸探针

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