Version 2.73

68466-2Epstein-Barr virus-encoded RNA 1 [Presence] in Tissue by ProbeActive

Term Descriptions

This term is used for the detection of nuclear Epstein-Barr virus-encoded RNA 1 (EBER1) by in situ hybridization on tissue. Presence of EBER1 indicates a latent EBV infection.
EBV encodes two small nuclear RNAs, EBER1 and EBER2, which are the most abundant viral transcripts in latently infected cells. They are non-polyadenylated and thus not translated into protein. Their function is to inhibit interferon-mediated antiviral effects and apoptosis. Since they are expressed at high levels (around a million copies per latently infected cell), they are considered to be an ideal marker of latent EBV infection. In situ hybridization targeting one or both EBERs is used to determine whether a biopsied tumor is EBV-related.
Source: Regenstrief LOINC

The Epstein-Barr virus (EBV), also called Human herpesvirus 4 (HHV-4), is a virus of the herpes family (which includes Herpes simplex virus and Cytomegalovirus). It is one of the most common viruses in humans. Individuals infected with EBV are often asymptomatic but EBV commonly causes infectious mononucleosis. It is named after Michael Epstein and Yvonne Barr, who together with Bert Achong discovered the virus in 1964.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Epstein barr virus (Wikipedia)

Fully-Specified Name

Epstein-Barr virus-encoded RNA 1

Additional Names

Short Name
EBV-encoded RNA1 Tiss Ql Probe
Display Name
EBV-encoded RNA 1 Probe Ql (Tiss)
Consumer Name Alpha
Epstein Barr virus (EBV)-encoded RNA 1, Tissue

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.38
Last Updated
Version 2.63
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
Epstein Barr 病毒编码型 RNA 1:存在情况或阈值:时间点:组织与涂片:序数型:DNA探针
nl-NLDutch (Netherlands)
Epstein-Barr-virus-encoded RNA 1:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:DNA-sonde
fr-FRFrench (France)
Epstein barr virus 1 ARN encodé:Présence/Seuil:Ponctuel:Tissu:Qualitatif:PCR
it-ITItalian (Italy)
Epstein-Barr virus, RNA 1 codificato:PrThr:Pt:Tessuto:Ord:Sonda
ru-RURussian (Russian Federation)
Эпштейн-Барр вирусом кодированная РНК 1:PrThr:ТчкВрм:Тк:Пор:Проба
es-MXSpanish (Mexico)
ARN 1 codificado por el virus de Epstein-Barr:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Investigacion
es-ESSpanish (Spain)
Virus Epstein-Barrs.ARN 1 codificado:PrThr:Punto temporal:Tejido:Ord:Sonda de DNA
tr-TRTurkish (Turkey)
Epstein-Barr virus-encoded RNA 1:MevcEşik:Zmlı:Doku:Srl:Prob

LOINC FHIR® API Example - CodeSystem Request Get Info