6864-3

Hemoglobin S [Presence] in Blood by Solubility test

Active

Part Description

LP16455-5 Hemoglobin S
Hemoglobin S (HbS) is a variant form of hemoglobin found in people with sickle cell disease. The Hb S variant occurs primarily among people of African, Hispanic, and Mediterranean descent. Hb S has a variation in the β-chain gene that causes a change in the properties of hemoglobin, resulting in abnormal, rigid, sickling shape of red blood cells. Individuals with two copies of the Hb S variant have classic sickle cell disease (sickle cell anemia, HbSS). Individuals with one HbS variant and one normal hemoglobin, Hb A, have sickle cell trait (HbAS) and usually have no associated symptoms. Hemoglobins exhibit different migration patterns in alkaline versus acidic electrophoresis conditions. So a combination of 2 procedures can be used in tandem to identify the hemoglobin variants. Source: Regenstrief LOINC , Sickle-cell disease (Wikipedia)

Reference Information

Type	Source	Reference
Mapping Guidance	Regenstrief Help	This solubility test is the standard method for detecting hemoglobin S. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

Fully-Specified Name

Component: Hemoglobin S
Property: PrThr
Time: Pt
System: Bld
Scale: Ord
Method: Solubility test

Additional Names

Long Common Name: Hemoglobin S [Presence] in Blood by Solubility test
Short Name: Hgb S Bld Ql Soly
Display Name: Hemoglobin S Solubility test Ql (Bld)
Consumer Name Alpha Get Info: Hemoglobin S, Blood

Basic Attributes

Class: HEM/BC
Type: Laboratory
First Released: Version 1.0h(2)
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 1295

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Hämoglobin S:Nachweis oder Schwellenwert:Zeitpunkt:Blut:Ordinal:Löslichkeitstest
el-GR	Greek (Greece)	Αιμοσφαιρίνη S:PrThr:Pt:Αίμα:Ord:Δοκιμή διαλυτότητας Synonyms: PrThr S Αιμοσφαιρίνη Αιμοσφαιρίνη S
es-AR	Spanish (Argentina)	hemoglobina S:concentración arbitraria:punto en el tiempo:sangre:ordinal:prueba de solubilidad
es-MX	Spanish (Mexico)	Hemoglobina S:Presencia o umbral:Punto temporal:Sangre:Ordinal:Prueba de solubilidad
es-ES	Spanish (Spain)	Hemoglobina S:PrThr:Punto temporal:Sangre:Ord:Test de solubilidad
fr-FR	French (France)	Hémoglobine S:Présence/Seuil:Ponctuel:Sang:Qualitatif:Test de solubilité
fr-BE	French (Belgium)	Hémoglobine S:PrThr:Temps ponctuel:Sang:Ordinal:Test de solubilité Synonyms: Hb HbS
fr-CA	French (Canada)	Hémoglobine S:Présence-Seuil:Temps ponctuel:Sang:Ordinal:Test de solubilité
it-IT	Italian (Italy)	Emoglobina S:PrThr:Pt:Sangue:Ord:Solubilità, test Synonyms: Ematologia (coagulazione) conta differenziale Presenza o Soglia Punto nel tempo (episodio) Sangue Test di solubilità
ko-KR	Korean (Korea, Republic Of)	혈색소 S:임의농도:검사시점:전혈:순위척도:용해도 검사
nl-NL	Dutch (Netherlands)	hemoglobine S:aanwezigheid:moment:bloed:ordinaal:oplosbaarheidstest
pl-PL	Polish (Poland)	Hemoglobina S:granica wykrywalności:punkt w czasie:krew:półilościowy:test rozpuszczalności
pt-BR	Portuguese (Brazil)	Hemoglobina S:ACnc:Pt:SgTotal:Ord:Teste de solubilidade Synonyms: ; Hgb S; Sickle cell; Sickle cells; HbS; Hb; Haemoglobin; Arbitrary concentration; Point in time; Random; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; Soly; S prime; HEMATOLOGY/CELL COUNTS; HEMATOLOGY/CELL COUNTS; Sickle cell screen; Sicklequik; Sickledex
ru-RU	Russian (Russian Federation)	Гемоглобин S:PrThr:ТчкВрм:Кр:Пор:Тест на растворимость Synonyms: Кровь Порядковый Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hemoglobin S:MevcEşik:Zmlı:Kan:Srl:Çözünebilirlik test Synonyms: Mevcut
uk-UA	Ukrainian (Ukraine)	Гемоглобін S:Наявність або Поріг:МоментЧасу:Кров:Порядково:Тест на розчинність Synonyms: Blood; Haemoglobin; Hb; HBs; HEMATOLOGY/CELL COUNTS; Hgb; Hgb S; Ordinal; Point in time; PR; QL; Qual; Qualitative; Random; S prime; Screen; Sickle cell; Sickle cell screen; Sickle cells; Sickledex; Sicklequik; Soly; UniversalLabOrders; WB; Whole blood
zh-CN	Chinese (China)	血红蛋白 S:存在情况或阈值:时间点:全血:序数型:溶解度试验 Synonyms: HbS;Hgb S;镰刀形红细胞;镰刀状红细胞;镰刀状细胞;镰状红细胞;镰状细胞 S 型依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型可溶性试验存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间氧血红蛋白;血红朊;血红素;血色素血;血液血液学/细胞计数;血液学与细胞计数血红蛋白S等级镰刀形红细胞筛查镰刀形红细胞筛查试验镰形细胞筛查镰形细胞筛查试验镰状红细胞筛查镰状红细胞筛查试验镰状细胞筛查镰状细胞筛查试验

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=6864-3

LOINC Copyright

Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.