68935-6
LDL.oxidized Ab [Units/volume] in Serum by Immunoassay
Active
Part Description
LP62198-4 LDL.oxidized
Once LDL accumulates in the subendothelial space, it tends to become modified or oxidized. This oxidized LDL plays several key roles in furthering the course of the inflammatory process. It is chemotactic to monocytes; oxidized LDL causes endothelial cells to secrete molecules that cause monocytes to penetrate between the endothelial cells and accumulate in the intima.
Oxidized LDL promotes death of endothelial cells by augmenting apoptosis. Also, through the activation of collagenases, ox-LDL contributes to a process which may lead to the rupture of the fibrous plaque. Oxidized LDL decreases the availability of endothelial nitric oxide (NO), which, in turn, increases the adhesion of monocytes to the endothelium. Moreover, NO is involved in paracrine signalling between the endothelium and the smooth muscle that maintains vascular tone; without it, the muscle will not relax, and the blood vessel remains constricted. Thus, oxidized LDL also contributes to the hypertension often seen with atherosclerosis.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Role of oxidized LDL
Fully-Specified Name
- Component
- LDL.oxidized Ab
- Property
- ACnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
- IA
Additional Names
- Short Name
- LDL.oxidized Ab Ser IA-aCnc
- Display Name
- LDL.oxidized Ab IA Qn (S)
- Consumer Name Alpha Get Info
- LDL.oxidized antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.38
- Last Updated
- Version 2.73
- Change Reason
- The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 14066
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG19294-4 | LDL.oxidized Ab| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | LDL. oxidadas Anticuerpos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Ab oxidado con LDL: |
| fr-CA | French (Canada) | LDL.oxydées , Ac: |
| fr-FR | French (France) | LDL oxydés anticorps: |
| fr-BE | French (Belgium) | LDL.oxydées Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | LDL.ossidato Ab: Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | LDL.geoxideerd As: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | ЛПНП.окисленные Ат: Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | LDL.okside Ab: Synonyms: Ak İmmünölçüm, immünoassay |
| zh-CN | Chinese (China) | 低密度脂蛋白.氧化型 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=68935-6
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright