Version 2.78

Part Descriptions

LP17722-7   Acetylcholine receptor
An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of the neurotransmitter acetylcholine. Nicotinic receptors are the primary mediator of the effects of nicotine. In myasthenia gravis, the receptor at the neuromuscular junction (NMJ) is targeted by antibodies, leading to muscle weakness. Muscarinic acetylcholine receptors can be blocked by the drugs atropine and scopolamine. Drugs such as the neuromuscular blocking agents bind reversibly to the nicotinic receptors in the neuromuscular junction and are used routinely in anesthesia. . Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Acetylcholine receptor (Wikipedia)

LP36947-7   Acetylcholine receptor Ab
AChR antibodies and striated muscle antibodies have been detected in patients with Myasthenia gravis (MG), thymoma without neurological symptoms, and in patients with other autoimmune diseases, including, for example, Lambert-Eaton disease, myasthenic syndrome, rheumatoid arthritis, systemic lupus erythematosus, Graves disease, and autoimmune liver disease.

AChR antibodies are further characterized into three categories; binding, blocking, and modulating.
ACHR-binding antibodies are detected in 90% of patients with severe, generalized MG, and 50% of patients with ocular MG. ACHR-modulating antibodies and ACHR-blocking antibodies are detected in approximately 65% to 70% of MG patients. Source: ARUP Laboratories

Fully-Specified Name

Component
Acetylcholine receptor Ab
Property
SCnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
AChR Ab Ser IA-sCnc
Display Name
Acetylcholine receptor Ab IA (S) [Moles/Vol]
Consumer Name Alpha Get Info
Acetylcholine receptor antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.70
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG6812-4 Acetylcholine receptor Ab|SCnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Receptor de acetilcolina Anticuerpos:Concentración de sustancia:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Receptor de acetilcolina Ab:Concentración de sustancias:Punto temporal:Suero:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Atsetüülkoliini retseptor antikehad:SCnc:Pt:S:Qn:IA
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Seerum
fr-CA French (Canada) Récepteur de l'acétylcholine, Ac:Concentration de substance:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR French (France) Acétylcholine récepteur anticorps:Moles/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE French (Belgium) Récepteur de l'acétylcholine Ac:Concentration de substance:Temps ponctuel:Sérum:Quantitatif:IA
Synonyms: Anticorps
it-IT Italian (Italy) Acetilcolina, recettore Ab:SCnc:Pt:Siero:Qn:IA
Synonyms: anticorpo Concentrazione di Sostanza Immunoassay Punto nel tempo (episodio) Recettore dell''acetilcolina Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) acetylcholinereceptor As:mol/volume:moment:serum:kwantitatief:immunoassay
Synonyms: acetylcholine receptor antistof; antilichaam IA
ru-RU Russian (Russian Federation) Ацетилхолин рецептор Ат:МолКонц:ТчкВрм:Сыв:Колич:IA
Synonyms: Антитело Ацетилхолиновый рецептор Количественный Молярность;Молярная объёмная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Asetilkolin reseptörü Ab:SubKons:Zmlı:Ser:Kant:İA
Synonyms: Ak İmmünölçüm, immünoassay
zh-CN Chinese (China) 乙酰胆碱受体 抗体:物质的量浓度:时间点:血清:定量型:免疫测定法
Synonyms: Ab;自身抗体 ACH;乙酰胆硷 AChR Ab AChR 抗体 AChR;乙酰胆碱受体（Acetylcholine Receptor，AChR） 乙酰胆碱受体 Ab 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
nmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=68937-2