6896-5

cloZAPine [Mass/volume] in Serum or Plasma

Active

Term Description

Per ARUP, clozapine levels are used to evaluate toxicity and monitor therapeutic drug levels. 100 ng/mL is the minimum therapeutic threshold, and levels > 1200 ng/mL increase the likelihood of adverse effects such as seizures.

Part Descriptions

LP17236-8 cloZAPine
Clozapine (sold as Clozaril ®, Leponex ®, Fazaclo ®) was the first of the atypical antipsychotics to be developed. It was approved by the United States Food and Drug Administration (FDA) in 1989 and is the only FDA-approved medication indicated for treatment-resistant schizophrenia and for reducing the risk of suicidal behaviour in patients with schizophrenia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Clozapine (Wikipedia)

LP17236-8 cloZAPine
A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent. Source: National Library of Medicine, MeSH 2006

LOINC Names Get Info

Fully-Specified Name: cloZAPine:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: cloZAPine [Mass/volume] in Serum or Plasma
Short Name: cloZAPine SerPl-mCnc
Display Name: cloZAPine [Mass/Vol]
Consumer Name Alpha Get Info: cloZAPine, Blood

Part Model Get Info

Component
cloZAPine
LP17236-8
- Analyte
  cloZAPine
  LP17236-8
  - Component Numerator
    cloZAPine
    LP17236-8
    - Component Numerator Core
      cloZAPine
      LP17236-8
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 1.0h(2)
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 2327

Member of these Panels

LOINC	Long Common Name
65632-2	cloZAPine and Norclozapine panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group	Group Name
LG48379-8	Clozapine\|Pt\|Ser/Plas

Language Variants Get Info

Tag	Language	Translation
ar-JO	Arabic (Jordan)	قياس مستوى الكلوزابين Synonyms: قياس مستوى الكلوزابين
cs-CZ	Czech (Czechia)	Klozapin:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
de-AT	German (Austria)	Synonyms: Clozapin
de-DE	German (Germany)	Clozapin:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
el-GR	Greek (Greece)	Κλοζαπίνη:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: DRUG/TOX MCnc Pt Qn Κλοζαπίνη Ορός Ορός/Πλάσμα Πλάσμα
es-AR	Spanish (Argentina)	clozapina:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES	Spanish (Spain)	Clozapina:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	clozapina:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE	Estonian (Estonia)	Klosapiin:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Clozapine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Clozapine:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Clozapine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Clozapina:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR	Korean (Korea, Republic Of)	클로자핀:질량농도:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	clozapine:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR	Portuguese (Brazil)	Clozapina:MCnc:Pt:Sor/Plas:Qn: Synonyms: Clozaril; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Клозапин:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Klozapine:KütlKons:Zmlı:Ser/Plaz:Kant:
uk-UA	Ukrainian (Ukraine)	клозапін:Масова Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно: Synonyms: Clozaril; DRUG/TOXICOLOGY; Drugs; FazaClo; Leponex; Level; Mass concentration; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; UniversalLabOrders
zh-CN	Chinese (China)	氯氮平:质量浓度:时间点:血清/血浆:定量型: Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类氯扎平水平;浓度;质量浓度(单位体积) 药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆

Example Units

Unit	Source
ng/mL	Example UCUM Units
ng/mL	REGENSTRIEF
ug/L	eCHN

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.