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Term Description

Note that both the numerator and denominator are concentration of the same protein in the CSF, ..BUT the denominator is the total CSF concentration and the numerator is the contribution of the protein in the CSF that is MADE IN THE CSF (i.e. "intrathecally") ---as opposed to protein that has diffused in from the blood. The calculation is IgX(Intracthecal fraction) = [IgX(Intrathecally synthsized concentration)/IgX(Total CSF Concentration)]*100 from "Multiple Sclerosis (1998) 4, 111 - 117"
From the same paper, the "IgX(Intrathecally synthsized concentration)" is complex to determine, but is based on the amount of protein in the CSF over and above that of the normal upper limit expected in the CSF (compared to that in blood). That 'over and above' amount is what is deemed to be produced in the CSF, which is the "Intrathecal Fraction"......
Same theme repeats in other papers (e.g. Am. J. Trop. Med. Hyg., 82(6), 2010, pp. 1094-1098)

LOINC Names Get Info

Fully-Specified Name
IgG.intrathecally synthesized/IgG.total:MFr:Pt:CSF:Qn:
Long Common Name
IgG.intrathecally synthesized/IgG.total in Cerebrospinal Fluid
Short Name
IgG.IT/IgG.total MFr CSF
Display Name
IgG.intrathecally synthesized/Total IgG (CSF) [Mass fraction]
Consumer Name Alpha Get Info
IgG.intrathecally synthesized/Total IgG, Spinal fluid

Part Model Get Info

  • Component
    IgG.intrathecally synthesized/IgG.total
    LP307479-8
    • Analyte
      IgG.intrathecally synthesized/IgG.total
      LP307479-8
      • Component Numerator
        IgG.intrathecally synthesized
        LP62859-1
        • Component Numerator Core
          IgG.intrathecally synthesized
          LP62859-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        IgG.total
        LP136492-8
        • Component Denominator Core
          IgG.total
          LP136492-8
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MFr
    LP6831-4
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.83 (MIN)
Order vs. Observation
Observation

Formula (Readable)

IgG(Intracthecal fraction) = [IgG(Intrathecally synthsized concentration)/IgG(Total CSF Concentration)]*100

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)IgG.intratekálně syntetizovaný/IgG.celkový:Hmotnostní podíl:Časový bod:Mozkomíšní mok:Kvantitativní:
de-ATGerman (Austria)Synonyms: IGG intrathek.Prod.%
el-GRGreek (Greece)IgG.ενδορραχιαίας σύνθεσης/IgG.ολική:MFr:Pt:ΕΝΥ:Qn:
Synonyms: CHEM IgG.ενδορραχιαίας σύνθεσης IgG.ολική MFr Pt Qn Ανοσοσφαιρίνη G ΕΝΥ
es-ESSpanish (Spain)IgG intratecal/IgG.total:Fracción de masa:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)IgG sintetizada por vía intratecal / IgG total:Fracción de masa:Punto temporal:Fluído espinal cerebral:Cuantitativo:
fr-FRFrench (France)Immunoglobuline G synthèse intrathécale/immunoglobuline G totale:Fraction massique:Ponctuel:Liquide céphalorachidien:Numérique:
it-ITItalian (Italy)IgG.IT/IgG.totali:MFr:Pt:LCS:Qn:
Synonyms: Chimica Frazione di massa IgG.intratecale Liquido cerebrospinale Punto nel tempo (episodio)
nl-NLDutch (Netherlands)IgG.intrathecale synthese/IgG.totaal:massafractie:moment:liquor cerebrospinalis:kwantitatief:
pl-PLPolish (Poland)IgG.syntetyzowane wewnątrzoponowo/IgG całkowite:frakcja masowa:punkt w czasie:płyn mózgowo-rdzeniowy:ilościowy:
Synonyms: IgG IgG syntetyzowane wewnątrzoponowo IgG syntetyzowane wewnątrzoponowo/IgG całkowite
ru-RURussian (Russian Federation)IgG.интратекально синтезированный/IgG.общий:МассДол:ТчкВрм:ЦСЖ:Колич:
Synonyms: IgG.синтезированный субдурально Количественный Массовая доля Точка во времени;Момент Цереброспинальная жидкость
tr-TRTurkish (Turkey)IgG.intrathekal sentezlenen/IgG.total:KütlFr:Zmlı:BOS:Kant:
zh-CNChinese (China)IgG.鞘内型/IgG.总计:质量分数:时间点:脑脊液:定量型:
Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 IgG.IT;IgG.鞘内;鞘内 IgG;鞘内产生型 IgG;鞘内型 IgG MFr 免疫球蛋白 G 免疫球蛋白 G;IgG 总计;总 IgG 全体数量 全部 共计 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 总 总和 总数 总量 总额 时刻;随机;随意;瞬间 汇总 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液

Example Units

UnitSource
%Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=68974-5