69003-2
Mononuclear cells atypical/100 leukocytes in Blood by Manual count
Active
Part Descriptions
LP35592-2 Mononuclear cells.atypical
A Peripheral Blood Mononuclear Cell (PBMC) is a blood cell having a round nucleus, such as a lymphocyte or a monocyte. These blood cells are a critical component in the immune system to fight infection and adapt to intruders. The lymphocyte population consists of T cells (CD4 and CD8 positive ~75%), B cells and NK cells (~25% combined).
These cells are often extracted from whole blood using ficoll, a hydrophilic polysaccharide that separates layers of blood, with monocytes and lymphocytes forming a buffy coat under a layer of plasma. This buffy coat contains the PBMCs. Additionally, PBMC can be extracted from whole blood using a hypotonic lysis which will preferentially lyse red blood cells. This method results in neutrophils and other polymorphonuclear (PMN) cells which are important in innate immune defense to be obtained.
PBMCs are widely used in research and clinical uses every day. HIV research uses them because PBMCs include CD4+ cells, the cells HIV infects.
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Source: Wikipedia, Mononuclear cell
LP35592-2 Mononuclear cells.atypical
Atypical mononuclear cells are morphologically abnormal lymphocytes or monocytes that may appear in a blood after immunizations or surgery, during infections, or at the onset of autoimmune diseases. Findings include primitive nuclei with a diffuse chromatin pattern and nucleoli, lobulated nuclei, and hyper-basophilic cytoplasm. The cells vary greatly in size and shape. Large numbers of atypical mononuclear cells can be seen with viral infections, including infectious mononucleosis (Epstein-Barr virus), infectious hepatitis (Hepatitis A virus) and bronchitis (adenovirus). Smaller numbers of atypical lymphocytes are seen in many other viral infections and in some bacterial and protozoan infections.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Mononuclear cells.atypical/100 leukocytes
- Property
- NFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
- Manual count
Additional Names
- Long Common Name
- Mononuclear cells atypical/100 leukocytes in Blood by Manual count
- Short Name
- Atypical Mononuc/leuk NFr Bld Manual
- Display Name
- Mononuclear cells atypical/100 WBC Manual cnt (Bld)
- Consumer Name Alpha Get Info
- Mononuclear cells atypical per 100 white blood cells, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.38
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 16620
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Células mononucleares atípicas/100 leucocitos: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Células mononucleares atípicas / 100 leucocitos: |
fr-CA | French (Canada) | Cellules mononucléaires.atypiques/100 leucocytes: |
fr-FR | French (France) | Cellules mononucluéées atypiques/100 leucocytes: |
fr-BE | French (Belgium) | Cellules mononucléaires.atypiques/100 leucocytes: Synonyms: Cellules mononucléées |
it-IT | Italian (Italy) | Cellule mononucleari.atipiche/100 leucociti: Synonyms: Cellule mononucleari atipiche Ematologia (coagulazione) conta differenziale Frazione numerica Punto nel tempo (episodio) Sangue |
nl-NL | Dutch (Netherlands) | mononucleaire cellen.atypisch/100 leukocyten: Synonyms: handmatige methode handmatige telling |
pl-PL | Polish (Poland) | Mononuklearne komórki.atypowe/100 leukocytów: Synonyms: Leukocyty Mononuklearne komórki Mononuklearne komórki atypowe Mononuklearne komórki atypowe/100 leukocytów |
ru-RU | Russian (Russian Federation) | Мононуклеарные клетки.атипичные/100 лейкоцитов: Synonyms: Количественный Количество отношение Кровь Точка во времени; |
tr-TR | Turkish (Turkey) | Mononükleer hücreler.atipik/100 lökosit: Synonyms: El ile |
zh-CN | Chinese (China) | 单个核细胞.异型/100 个白细胞: Synonyms: 100 WBC Leuc; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
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