Version 2.80

Part Descriptions

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

LP35592-2   Mononuclear cells.atypical
A Peripheral Blood Mononuclear Cell (PBMC) is a blood cell having a round nucleus, such as a lymphocyte or a monocyte. These blood cells are a critical component in the immune system to fight infection and adapt to intruders. The lymphocyte population consists of T cells (CD4 and CD8 positive ~75%), B cells and NK cells (~25% combined).

These cells are often extracted from whole blood using ficoll, a hydrophilic polysaccharide that separates layers of blood, with monocytes and lymphocytes forming a buffy coat under a layer of plasma. This buffy coat contains the PBMCs. Additionally, PBMC can be extracted from whole blood using a hypotonic lysis which will preferentially lyse red blood cells. This method results in neutrophils and other polymorphonuclear (PMN) cells which are important in innate immune defense to be obtained.

PBMCs are widely used in research and clinical uses every day. HIV research uses them because PBMCs include CD4+ cells, the cells HIV infects. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Mononuclear cell

LP35592-2   Mononuclear cells.atypical
Atypical mononuclear cells are morphologically abnormal lymphocytes or monocytes that may appear in a blood after immunizations or surgery, during infections, or at the onset of autoimmune diseases. Findings include primitive nuclei with a diffuse chromatin pattern and nucleoli, lobulated nuclei, and hyper-basophilic cytoplasm. The cells vary greatly in size and shape. Large numbers of atypical mononuclear cells can be seen with viral infections, including infectious mononucleosis (Epstein-Barr virus), infectious hepatitis (Hepatitis A virus) and bronchitis (adenovirus). Smaller numbers of atypical lymphocytes are seen in many other viral infections and in some bacterial and protozoan infections. Source: Regenstrief LOINC

Fully-Specified Name

Component
Mononuclear cells.atypical/Leukocytes
Property
NFr
Time
Pt
System
Bld
Scale
Qn
Method
Manual count

Additional Names

Long Common Name
Mononuclear cells atypical/Leukocytes in Blood by Manual count
Short Name
Atypical Mononuc NFr Bld Manual
Display Name
Mononuclear cells atypical/Leukocytes Manual cnt (Bld)
Consumer Name Alpha Get Info
Mononuclear cells atypical/White Blood Cells, Blood

Basic Attributes

Class
HEM/BC
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Observation
Common Test Rank Get Info
16620

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Μονοπύρηνα κύτταρα.άτυπα/Λευκοκύτταρα:NFr:Pt:Αίμα:Qn:Χειροκίνητη καταμέτρηση
Synonyms: NFr Κύτταρα Λευκοκύτταρα Μονοπύρηνα κύτταρα Μονοπύρηνα κύτταρα.άτυπα
es-ES Spanish (Spain) Células mononucleares atípicas/Leucocitos:Fracción numérica:Punto temporal:Sangre:Qn:Contaje manual
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Células mononucleares atípicas / 100 leucocitos:Fracción numérica:Punto temporal:Sangre:Cuantitativo:Conteo manual
fr-CA French (Canada) Cellules mononucléaires.atypiques/Leucocytes:Fraction numérique:Temps ponctuel:Sang:Quantitatif:Numération manuelle
fr-FR French (France) Cellules mononucluéées atypiques/100 leucocytes:Fraction de nombres:Ponctuel:Sang:Numérique:Comptage manuel
it-IT Italian (Italy) Cellule mononucleari.atipiche/Leucociti:NFr:Pt:Sangue:Qn:Conta manuale
Synonyms: Cellule mononucleari atipiche Ematologia (coagulazione) conta differenziale Frazione numerica Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) mononucleaire cellen.atypisch/leukocyten:getalsfractie:moment:bloed:kwantitatief:manuele telling
Synonyms: handmatige methode handmatige telling
pl-PL Polish (Poland) Mononuklearne komórki.atypowe/leukocyty:frakcja liczbowa:punkt w czasie:krew:ilościowy:zliczanie ręczne
Synonyms: Leukocyty Mononuklearne komórki Mononuklearne komórki atypowe
ru-RU Russian (Russian Federation) Мононуклеарные клетки.атипичные/Лейкоциты:КолДоля:ТчкВрм:Кр:Колич:Ручной подсчет
Synonyms: Количественный Количество отношение Кровь Точка во времени;Момент
tr-TR Turkish (Turkey) Mononükleer hücreler.atipik/Lökosit:SayFr:Zmlı:Kan:Kant:Manuel sayım
Synonyms: El ile
zh-CN Chinese (China) 单个核细胞.异型/白细胞:计数型分数:时间点:全血:定量型:手工计数方法
Synonyms: Leuc;Leuk;Lkcs;WBC;WBCs;白细胞;White blood cell;WBC;白细胞类;白细胞类髓系细胞;白血球;白血细胞;白细胞数 不典型 不典型单个核细胞;单个核细胞.不典型;单个核细胞.非典型;异型单个核细胞;非典型单个核细胞 不典型的 人工计数;人工计数方法;人工计数法;手工计数;手工计数法 单个核 反应性 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实验室手工方法;手工;手工法;手工类实验室方法;手工类方法;手工类检验方法 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 血;血液 血液学/细胞计数;血液学与细胞计数 非典型 非典型的

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=69003-2