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Part Descriptions

LP18408-2   2-Oxoadipate
α-Ketoadipic acid (or 2-oxoadipate) is an intermediate in the metabolism of lysine. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP18408-2   2-Oxoadipate
2-Oxoadipic acid is produced from lysine in the cytosol of cells via the saccharopine and the pipecolic acid pathways. Catabolites of hydroxylysine and tryptophan enter these pathways as 2-aminoadipic- -semialdehyde and 2-oxoadipate, respectively. In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. 2-Oxoadipic aciduria is an in-born error of metabolism of lysine, tryptophan, and hydroxylysine, in which abnormal quantities of 2-aminoadipic acid are found in body fluids along with 2-oxoadipic acid. Patients with 2-Oxoadipic acidemias are mentally retarded with hypotonia or seizures. 2-Oxoadipic Aciduria can occur in patients with Kearns-Sayre Syndrome, a progressive disorder with onset prior to 20 years of age in which multiple organ systems are affected, including progressive external ophthalmoplegia, retinopathy, and the age of onset, and these are associated classically with abnormalities in cardiac conduction, cerebellar signs, and elevated cerebrospinal fluid protein. PMID: 10655159, PMID: 16183823, PMID: 11083877 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database

LOINC Names Get Info

Fully-Specified Name
2-Oxoadipate:SCnc:Pt:Ser/Plas:Qn:
Long Common Name
2-Oxoadipate [Moles/volume] in Serum or Plasma
Short Name
2-Oxoadipate SerPl-sCnc
Display Name
2-Oxoadipate [Moles/Vol]
Consumer Name Alpha Get Info
2-Oxoadipate, Blood

Part Model Get Info

  • Component
    2-Oxoadipate
    LP18408-2
    • Analyte
      2-Oxoadipate
      LP18408-2
      • Component Numerator
        2-Oxoadipate
        LP18408-2
        • Component Numerator Core
          2-Oxoadipate
          LP18408-2
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)2-oxoadipát:Látková koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)2-οξο-αδιπικό:SCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: 2-οξο-αδιπικό CHEM Pt Qn SCnc Ορός Ορός/Πλάσμα Πλάσμα
es-ESSpanish (Spain)2-Oxoadipato:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)2-oxoadipato:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
et-EEEstonian (Estonia)2-oksoadipaat:SCnc:Pt:S/P:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CAFrench (Canada)2-oxoadipate:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)2-oxoadipate:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BEFrench (Belgium)2-oxoadipate:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-ITItalian (Italy)2-Ossoadipato:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NLDutch (Netherlands)2-oxoadipaat:mol/volume:moment:serum of plasma:kwantitatief:
pl-PLPolish (Poland)2-Oksoadypinian:stężenie molowe:punkt w czasie:surowica lub osocze:ilościowy:
ru-RURussian (Russian Federation)2-Оксоадипат:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)2-Okzoadipat:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CNChinese (China)2-氧代己二酸:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 2Oxo-己二酸 Ⅱ II 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清或血浆

Example Units

UnitSource
umol/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=69768-0