69801-9
2-Oxoadipate [Moles/volume] in Cerebrospinal Fluid
Active
Part Descriptions
LP18408-2 2-Oxoadipate
α-Ketoadipic acid (or 2-oxoadipate) is an intermediate in the metabolism of lysine.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Wikipedia
LP18408-2 2-Oxoadipate
2-Oxoadipic acid is produced from lysine in the cytosol of cells via the saccharopine and the pipecolic acid pathways. Catabolites of hydroxylysine and tryptophan enter these pathways as 2-aminoadipic- -semialdehyde and 2-oxoadipate, respectively. In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. 2-Oxoadipic aciduria is an in-born error of metabolism of lysine, tryptophan, and hydroxylysine, in which abnormal quantities of 2-aminoadipic acid are found in body fluids along with 2-oxoadipic acid. Patients with 2-Oxoadipic acidemias are mentally retarded with hypotonia or seizures. 2-Oxoadipic Aciduria can occur in patients with Kearns-Sayre Syndrome, a progressive disorder with onset prior to 20 years of age in which multiple organ systems are affected, including progressive external ophthalmoplegia, retinopathy, and the age of onset, and these are associated classically with abnormalities in cardiac conduction, cerebellar signs, and elevated cerebrospinal fluid protein. PMID: 10655159, PMID: 16183823, PMID: 11083877
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
LOINC Names Get Info
- Fully-Specified Name
- 2-Oxoadipate:
SCnc: Pt: CSF: Qn: - Long Common Name
- 2-Oxoadipate [Moles/volume] in Cerebrospinal Fluid
- Short Name
- 2-Oxoadipate CSF-sCnc
- Display Name
- 2-Oxoadipate (CSF) [Moles/Vol]
- Consumer Name Alpha Get Info
- 2-Oxoadipate, Spinal fluid
Part Model Get Info
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.40
- Last Updated
- Version 2.83 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | 2-oxoadipát: |
| el-GR | Greek (Greece) | 2-οξο-αδιπικό: Synonyms: 2-οξο-αδιπικό CHEM Pt Qn SCnc ΕΝΥ |
| es-ES | Spanish (Spain) | 2-Oxoadipato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | 2-oxoadipato: |
| et-EE | Estonian (Estonia) | 2-oksoadipaat: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Liikvor |
| fr-CA | French (Canada) | 2-oxoadipate: |
| fr-FR | French (France) | 2-oxoadipate: |
| fr-BE | French (Belgium) | 2-oxoadipate: |
| it-IT | Italian (Italy) | 2-Ossoadipato: Synonyms: Chimica Concentrazione di Sostanza Liquido cerebrospinale Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | 2-oxoadipaat: |
| pl-PL | Polish (Poland) | 2-Oksoadypinian: |
| ru-RU | Russian (Russian Federation) | 2-Оксоадипат: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | 2-Okzoadipat: |
| zh-CN | Chinese (China) | 2-氧代己二酸: Synonyms: 2Oxo-己二酸 Ⅱ CSF CSF; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://