Version 2.78

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus Ab.IgM
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IA

Additional Names

Short Name
VZV IgM CSF Ql IA
Display Name
VZV IgM IA Ql (CSF)
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox) IgM antibody, Spinal fluid

Example Answer List: LL2010-8

Source: Estonian Society of Laboratory Medicine
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Borderline LA4259-3

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.68
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32750-8 Varicella zoster virus

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Varizella-Zoster-Virus-AK IgM ql. /L
de-DE German (Germany) Varicella-Zoster-Virus Ak.IgM:Nachweis oder Schwellenwert:Zeitpunkt:Liquor:Ordinal:Immunoassay
Synonyms: Human alphaherpesvirus 3; VZV; Zerebrospinalflüssigkeit
el-GR Greek (Greece) Ιός ανεμευλογιάς-έρπητα ζωστήρα IgM ανοσοσφαιρίνη:PrThr:Χρονική στιγμή:ΕΝΥ:Τακτική:IA
Synonyms: Ab IgM VZV
es-ES Spanish (Spain) Virus Varicella zoster IgM:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:IA
es-MX Spanish (Mexico) Ab.IgM del virus de la varicela zóster:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunoensayo
et-EE Estonian (Estonia) Tuulerõugeviirus antikehad.IgM:PrThr:Pt:CSF:Ord:IA
Synonyms: Immuunglobuliin M Järgarvuline Juhuslik Liikvor
fr-CA French (Canada) Virus varicelle-zona, IgM:Présence-Seuil:Temps ponctuel:LCR:Ordinal:IA
fr-FR French (France) Varicelle zona virus Ac IgM:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunoanalyse
fr-BE French (Belgium) Virus varicelle-zona Anticorps. IgM:PrThr:Temps ponctuel:LCR:Ordinal:IA
Synonyms: Anticorps VZV
it-IT Italian (Italy) Varicella zoster, virus Ab.IgM:PrThr:Pt:LCS:Ord:IA
Synonyms: Anticorpi IgM anticorpo Immunoassay Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Virus della varicella zoster
nl-NL Dutch (Netherlands) varicella-zostervirus As.IgM:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA Varicella zoster virus
pt-BR Portuguese (Brazil) Varicella zoster vírus Ac.IgM:Limiar:Pt:LCR:Ord:Imunoensaio
ru-RU Russian (Russian Federation) Varicella zoster вирус Ат.IgM:PrThr:ТчкВрм:ЦСЖ:Пор:IA
Synonyms: Антитело Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Varicella zoster virüsü Ab.IgM:MevcEşik:Zmlı:BOS:Srl:İA
Synonyms: Ak Ak.IgM İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) 水痘带状疱疹病毒 抗体.IgM:存在情况或阈值:时间点:脑脊液:序数型:免疫测定法
Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 HHV-3 Ab HHV-3 Ab.IgM HHV-3 抗体 HHV-3 抗体.IgM HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 VZV Ab VZV Ab.IgM VZV 抗体 VZV 抗体.IgM 人类疱疹病毒 3 型 Ab 人类疱疹病毒 3 型 Ab.IgM 人类疱疹病毒 3 型抗体 人类疱疹病毒 3 型抗体.IgM 人类疱疹病毒 III 型 Ab 人类疱疹病毒 III 型 Ab.IgM 人类疱疹病毒 III 型抗体 人类疱疹病毒 III 型抗体.IgM 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 M 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 水痘带状疱疹病毒 Ab 水痘带状疱疹病毒 Ab.IgM 水痘带状疱疹病毒 IgM 水痘病毒 Ab 水痘病毒 Ab.IgM 水痘病毒抗体 水痘病毒抗体.IgM 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=69930-6