Version 2.67

70163-1Chlamydia trachomatis and Neisseria gonorrhoeae rRNA panel - Cervix by NAA with probe detectionActive

Term Description

This panel was created based on Gen-Probe APTIMA COMBO 2 Assay. The test is used for detection and differentiation of ribosomal RNA (rRNA) from Chlamydia trachomatis and/or Neisseria gonorrhoeae.
Source: Regenstrief LOINC

Part Description

LP115366-9   Chlamydia trachomatis & Neisseria gonorrhoeae rRNA panel
Target amplification assays are based on the ability of complementary oligonucleotide primers to specifically anneal and allow enzymatic amplification of the target nucleic acid strands. The GEN-PROBE APTIMA Combo 2 Assay replicates a specific region of the 23S rRNA from CT and a specific region of the 16S rRNA from GC via DNA intermediates. A unique set of primers is used for each target molecule. Detection of the rRNA amplification product sequences (amplicon) is achieved using nucleic acid hybridization. Single-stranded chemiluminescent DNA probes, which are complementary to a region of each target amplicon, are labeled with different acridinium ester molecules. The labeled DNA probes combine with amplicon to form stable RNA:DNA hybrids. The Selection Reagent differentiates hybridized from unhybridized probe, eliminating the generation of signal from unhybridized probe. During the detection step, light emitted from the labeled RNA:DNA hybrids is measured as photon signals in a luminometer, and are reported as Relative Light Units (RLU). In DKA, differences in the kinetic profiles of the CT and GC labeled probes allow for the differentiation of signal; kinetic profiles are derived from measurements of photon output during the detection read time. The chemiluminescent detection reaction for CT signal has very rapid kinetics and has the "flasher" kinetic type. The chemiluminescent detection reaction for GC signal is relatively slower and has the "glower" kinetic type. Assay results are determined by a cut-off based on the total RLU and the kinetic curve type. Source: Regenstrief Help

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
70163-1 Chlamydia trachomatis and Neisseria gonorrhoeae rRNA panel - Cervix by NAA with probe detection
Indent50387-0 Chlamydia trachomatis rRNA [Presence] in Cervix by NAA with probe detection R
Indent50388-8 Neisseria gonorrhoeae rRNA [Presence] in Cervix by NAA with probe detection R

Fully-Specified Name

Chlamydia trachomatis & Neisseria gonorrhoeae rRNA panel

Additional Names

Short Name
C trach+GC pnl Cvx NAA+probe
Display Name
C. trachomatis and N. gonorrhoeae rRNA panel NAA+probe (Cvx)

Basic Attributes

First Released
Version 2.40
Last Updated
Version 2.63
Order vs. Observation
Panel Type

Reference Information

Type Source Reference
Package Insert Gen-Probe Example package insert. This LOINC code is not constrained to this specific product. APTIMA COMBO 2® Assay

Language Variants Get Info

zh-CNChinese (CHINA)
沙眼衣原体与淋病奈瑟菌 rRNA 组套:-:时间点:子宫颈:-:探针法.基因扩增.靶向
Chlamydia trachomatis & Neisseria gonorrhoeae rRNA panel:-:moment:cervix:-:moleculaire techniek (PCR)
fr-CAFrench (CANADA)
Chlamydia trachomatis & Neisseria gonorrhoeae, ARNr:-:Temps ponctuel:Col de l'utérus:-:Sonde avec amplification de la cible
fr-FRFrench (FRANCE)
Chlamydia trachomatis et Neisseria gonorrhoeae ARNr panel:-:Ponctuel:Col de l'utérus:-:PCR amplification de cible
it-ITItalian (ITALY)
Chlamydia trachomatis & Neisseria gonorrhoeae, panel rRNA:-:Pt:Cvx:-:Sonda.amp.tar
pt-BRPortuguese (BRAZIL)
Chlamydia trachomatis & Neisseria gonorrhoeae рРНК панель:-:ТчкВрм:Шейка:-:Проба.усил.миш
es-ESSpanish (SPAIN)
Perfil de rRNA de Chlamydia trachomatis y Neisseria gonorrhoeae:Propiedades mixtas (sólo paneles):Punto temporal:Cuello uterino:-:Sonda con amplificación dirigida

LOINC FHIR® API Example - CodeSystem Request Get Info