Version 2.78

Term Description

This panel was created based on Gen-Probe APTIMA COMBO 2 Assay. The test is used for detection and differentiation of ribosomal RNA (rRNA) from Chlamydia trachomatis and/or Neisseria gonorrhoeae.
Source: Regenstrief LOINC

Part Description

LP115366-9   Chlamydia trachomatis & Neisseria gonorrhoeae rRNA panel
Target amplification assays are based on the ability of complementary oligonucleotide primers to specifically anneal and allow enzymatic amplification of the target nucleic acid strands. The GEN-PROBE APTIMA Combo 2 Assay replicates a specific region of the 23S rRNA from CT and a specific region of the 16S rRNA from GC via DNA intermediates. A unique set of primers is used for each target molecule. Detection of the rRNA amplification product sequences (amplicon) is achieved using nucleic acid hybridization. Single-stranded chemiluminescent DNA probes, which are complementary to a region of each target amplicon, are labeled with different acridinium ester molecules. The labeled DNA probes combine with amplicon to form stable RNA:DNA hybrids. The Selection Reagent differentiates hybridized from unhybridized probe, eliminating the generation of signal from unhybridized probe. During the detection step, light emitted from the labeled RNA:DNA hybrids is measured as photon signals in a luminometer, and are reported as Relative Light Units (RLU). In DKA, differences in the kinetic profiles of the CT and GC labeled probes allow for the differentiation of signal; kinetic profiles are derived from measurements of photon output during the detection read time. The chemiluminescent detection reaction for CT signal has very rapid kinetics and has the "flasher" kinetic type. The chemiluminescent detection reaction for GC signal is relatively slower and has the "glower" kinetic type. Assay results are determined by a cut-off based on the total RLU and the kinetic curve type. Source: Regenstrief Help

Reference Information

Type Source Reference
Package Insert Gen-Probe Example package insert. This LOINC code is not constrained to this specific product. APTIMA COMBO 2® Assay

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
70164-9 Chlamydia trachomatis and Neisseria gonorrhoeae rRNA panel - Vaginal fluid by NAA with probe detection
Indent53926-2 Chlamydia trachomatis rRNA [Presence] in Vaginal fluid by NAA with probe detection R
Indent53879-3 Neisseria gonorrhoeae rRNA [Presence] in Vaginal fluid by NAA with probe detection R

Fully-Specified Name

Component
Chlamydia trachomatis & Neisseria gonorrhoeae rRNA panel
Property
-
Time
Pt
System
Vag
Scale
-
Method
Probe.amp.tar

Additional Names

Short Name
C trach+GC pnl Vag NAA+probe
Display Name
C. trachomatis and N. gonorrhoeae rRNA panel NAA+probe (Vag fld)
Consumer Name Alpha Get Info
Chlamydia trachomatis and Neisseria gonorrhoeae panel, Vaginal fluid

Basic Attributes

Class
PANEL.MICRO
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.73
Order vs. Observation
Order
Common Test Rank Get Info
12670
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Perfil de rRNA de Chlamydia trachomatis y Neisseria gonorrhoeae:Propiedades mixtas (sólo paneles):Punto temporal:Vaginal:-:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Panel de ARNr de Chlamydia trachomatis y Neisseria gonorrhoeae:-:Punto temporal:Vaginal:-:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Chlamydia trachomatis & Neisseria gonorrhoeae, ARNr:-:Temps ponctuel:Vaginal:-:Sonde avec amplification de la cible
fr-FR French (France) Chlamydia trachomatis et Neisseria gonorrhoeae ARNr panel:-:Ponctuel:Prélèvement vaginal:-:PCR amplification de cible
it-IT Italian (Italy) Chlamydia trachomatis & Neisseria gonorrhoeae, panel rRNA:-:Pt:Vaginale:-:Sonda.amp.tar
Synonyms: Chlamydia trachomatis e Neisseria gonorrhoeae Microbiologia Panel rRNA Chlamydia trachomatis e Neisseria gonor Punto nel tempo (episodio) Set di prescrizione microbiologia Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Vaginale
nl-NL Dutch (Netherlands) Chlamydia trachomatis & Neisseria gonorrhoeae rRNA panel:-:moment:vaginaal monster:-:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Chlamydia trachomatis & Neisseria gonorrhoeae rRNA painel::Pt:Vagina:-:Sonda com limite de detecção da amplificação de alvo
ru-RU Russian (Russian Federation) Chlamydia trachomatis & Neisseria gonorrhoeae рРНК панель:-:ТчкВрм:Вагин:-:Проба.усил.миш
Synonyms: Вагинальный ДНК проба;ДНК зонд Проба с мишени усилением Точка во времени;Момент
zh-CN Chinese (China) 沙眼衣原体与淋病奈瑟菌 rRNA 组套:-:时间点:阴道:-:探针法.基因扩增.靶向
Synonyms: Gen-Probe rRNA 探针法.扩增.靶向 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.微生物学;实验室组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）类.微生物学试验;医嘱组.微生物学试验;医嘱组类.微生物学;医嘱组类.微生物学试验;实验室医嘱组类.微生物学;微生物学医嘱组;微生物学医嘱组类 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 基因探针 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 核糖体 RNA 探针法.基因扩增.靶向 核糖体 RNA 探针法.扩增.靶向 核糖体核糖核酸 探针法.基因扩增.靶向 核糖体核糖核酸 探针法.扩增.靶向 核蛋白体 RNA 核蛋白体 RNA 探针法.基因扩增.靶向 核蛋白体 RNA 探针法.扩增.靶向 核蛋白体 RNA（Ribosomal RNA，RRNA） 核蛋白体核糖核酸 核醣体 RNA 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 椒疮;沙眼;砂眼;粒性结膜炎;颗粒性结膜炎 沙眼衣原体+淋病奈瑟菌（淋球菌、淋病、淋病双球菌、淋病奈瑟氏菌）;C trach+GC;CT/GC 沙眼衣原体与淋病奈瑟菌（淋球菌、淋病、淋病双球菌、淋病奈瑟氏菌） 沙眼衣原体与淋病奈瑟菌（淋球菌、淋病、淋病双球菌、淋病奈瑟氏菌） rRNA 组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;沙眼衣原体与淋病奈瑟菌 rRNA 组套;沙眼衣原体与淋病奈瑟菌 rRNA 组合;沙眼衣原体与淋病奈瑟菌核糖体核糖核酸医嘱组 淋球菌 rRNA 淋球菌;淋病;淋病双球菌;淋病奈瑟氏菌 淋病奈瑟氏菌 rRNA 组 组合 组合医嘱 组合类 组套 经过扩增的 脱氧核糖核酸探针 衣原体属 阴道分泌物;白带;阴道标本;阴道病理标本

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=70164-9
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/70164-9