70256-3

Nuclear IgG Ab [Ratio] in Serum by Immunoassay

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Term Description

This term was created for (but not limited to) Euroimmun's ANA Screen ELISA (IgG) test kit, a semi-quantitative in vitro assay of a pool of human nuclear autoantibodies (IgG) against ten different antigens, including double-stranded DNA (dsDNA), histones, ribosomal P-proteins, nRNP, Sm, SS-A, SS-B, Scl-70, Jo-1 and centromeres. Semi-quantitative results are determined by the ratio of the extinction of the calibrator (cut-off) to the extinction of control or patient samples. A ratio of 1.0 or greater is a positive result, which is associated conditions such as Sharp syndrome (MCTD), Systemic lupus erythematosus, Sjögren's syndrome, Progressive systemic sclerosis, and Poly-dermatomyositis.

Part Description

LP16670-9 Nuclear
The nucleus of a cell contains the body's genetic material. It is the site of transcriptional regulation, RNA processing and DNA synthesis and transcription.
PMID: 24563360 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Nuclear Ab.IgG:Ratio:Pt:Ser:Qn:IA
Long Common Name: Nuclear IgG Ab [Ratio] in Serum by Immunoassay
Short Name: Nuclear IgG Ser IA-Rto
Display Name: Nuclear IgG IA (S) [Ratio]
Consumer Name Alpha Get Info: Nuclear IgG antibody, Blood

Part Model Get Info

Component
Nuclear Ab.IgG
LP39214-9
- Analyte
  Nuclear Ab.IgG
  LP39214-9
  - Component Numerator
    Nuclear Ab.IgG
    LP39214-9
    - Component Numerator Core
      Nuclear
      LP16670-9
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Ratio
LP6852-0
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.40
Last Updated: Version 2.70 (MIN)
Change Reason: The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Formula (Readable)

Extinction of the calibrator (cut - off)/Extinction of control or patient samples = Ratio

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Antinukleární protilátky IgG:Poměr:Časový bod:Sérum:Kvantitativní:Imunoanalýza
el-GR	Greek (Greece)	Πυρηνικό Αντισώματα IgG:Ratio:Pt:Ορός:Qn:IA Synonyms: IA Pt Qn Ratio SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Ορός Πυρηνικό
es-ES	Spanish (Spain)	Nuclear IgG:Fracción:Punto temporal:Suero:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Ab.IgG nuclear:Proporción:Punto temporal:Suero:Cuantitativo:Inmunoensayo
et-EE	Estonian (Estonia)	Tuumavastased antikehad.IgG:Suhe:Pt:S:Qn:IA Synonyms: Immuunglobuliin G Juhuslik Kvantitatiivne Seerum
fr-CA	French (Canada)	Nucléaire, IgG:Ratios:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR	French (France)	Noyau Ac IgG:Ratio:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE	French (Belgium)	Nucléaire Anticorps. IgG:Ratios:Temps ponctuel:Sérum:Quantitatif:IA Synonyms: Anticorps
it-IT	Italian (Italy)	Nucleare Ab.IgG:Rapporto:Pt:Siero:Qn:IA Synonyms: anticorpi IgG anticorpo Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	nucleaire As.IgG:verhouding:moment:serum:kwantitatief:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	Jądrowy Ab.IgG:współczynnik:punkt w czasie:surowica:ilościowy:metoda immunologiczna Synonyms: IgG przeciwciała IgG Przeciwciała IgG do jądra komórkowego Przeciwciała przeciwjądrowe
ru-RU	Russian (Russian Federation)	Ядерный Ат.IgG:Отношение:ТчкВрм:Сыв:Колич:IA Synonyms: Антитело Количественный Коэффициент;Соотношение;Пропорция Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Nükleer Ab.IgG:Oran:Zmlı:Ser:Kant:İA Synonyms: Ak Ak.IgG Çekirdek İmmünölçüm, immünoassay
zh-CN	Chinese (China)	细胞核抗体.IgG:比率:时间点:血清:定量型:免疫测定法 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 ANA NA 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 G 可用数量表示的;定量性;数值型;数量型;连续数值型标尺抗核 Ab 抗核抗体抗核抗体（Antinuclear antibody，ANA）时刻;随机;随意;瞬间来自于不同体系的两个观察指标之比;比;比值核;胞核核心抗体IgG 核心抗原抗体.IgG 核心抗原抗体IgG 核抗体.IgG 核抗体IgG 核抗原抗体.IgG 核抗原抗体IgG 细胞核 Ab 细胞核 Ab.IgG 细胞核 IgG 胞核 Ab 胞核 Ab.IgG 胞核抗体胞核抗体.IgG 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit	Source
[arb'U]	Example UCUM Units

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.