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Term Description

This term is used to identify a leukemia causing chromosomal translocation resulting in a gene fusion between FUS (16p11.2) and ERG (21q22) genes. The term was created for (but not limited to) DNA Technology's HemaVision HV01-28N kit, a qualitative in vitro diagnostic test for 28 leukemia causing chromosomal alterations including more than 80 breakpoints plus associated mRNA splice variants. Reverse transcription followed by multiplex nested polymerase chain reactions (RT-PCR) and agarose gel electrophoresis are used to identify gene fusions caused by chromosomal translocations, gene deletions or inversions. Testing information is useful for predicting development of the disease and selection of treatment.

LOINC Names Get Info

Fully-Specified Name
t(16;21)(p11.2;q22.3)(FUS,ERG) fusion transcript:Arb:Pt:Bld/Tiss:Ord:Molgen
Long Common Name
t(16;21)(p11.2;q22.3)(FUS,ERG) fusion transcript [Presence] in Blood or Tissue by Molecular genetics method
Short Name
t(16;21)(FUS,ERG) Bld/T Ql
Display Name
t(16;21)(p11.2;q22.3)(FUS,ERG) fusion transcript Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
t(16;21)(p11.2;q22.3)(FUS,ERG) fusion transcript analysis, Blood or tissue specimen

Part Model Get Info

  • Component
    t(16;21)(p11.2;q22.3)(FUS,ERG) fusion transcript
    LP229746-5
    • Analyte
      t(16;21)(p11.2;q22.3)(FUS,ERG) fusion transcript
      LP229746-5
      • Component Numerator
        t(16;21)(p11.2;q22.3)(FUS,ERG) fusion transcript
        LP229746-5
        • Component Numerator Core
          t(16;21)(p11.2;q22.3)(FUS,ERG)
          LP146057-7
        • Component Numerator Core Suffix
          fusion transcript
          LP150217-0
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Arb
    LP6781-1
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Molgen
    LP6404-0

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.40 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
72103-5Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Fúzní transkript t(16;21)(p11.2;q22.3)(FUS,ERG):Arbitrární:Časový bod:Krev/tkáň:Ordinální:Molekulární genetika
el-GRGreek (Greece)t(16;21)(p11.2;q22.3)(FUS,ERG) μεταγραφή συγχώνευσης:Arb:Pt:Αίμα/Ιστός:Ord:Μοριακή γενετική
Synonyms: Arb MOLPATH MOLPATH.TRNLOC Ord Pt t(16;21)(p11.2;q22.3)(FUS,ERG) Αίμα Αίμα/Ιστός Ιστός μεταγραφή συγχώνευσης Μοριακή γενετική
es-ESSpanish (Spain)t(16;21)(p11.2;q22.3)(FUS,ERG) Tránscritos de fusión:Arbitrario:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MXSpanish (Mexico)t (16; 21) (p11.2; q22.3) (FUS, ERG) transcripción de fusión:Arbitrario:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-CAFrench (Canada)t(16;21)(p11.2;q22.3)(FUS,ERG) transcrit de fusion:Arbitraire:Temps ponctuel:Sang/Tissu:Ordinal:Molgen
fr-FRFrench (France)t(16;21)(p11.2;q22.3)(FUS,ERG) transcript de fusion:Arbitraire:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-ITItalian (Italy)t(16,21)(p11.2,q22.3)(FUS,ERG), trascritto di fusione:Arb:Pt:Sangue/Tess:Ord:Molgen
Synonyms: Arbitrario Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NLDutch (Netherlands)t(16;21)(p11.2;q22.3)(FUS,ERG) fusietranscript:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: molgen
ru-RURussian (Russian Federation)t(16;21)(p11.2;q22.3)(FUS,ERG) слияния транскрипт:Произв:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Произвольный Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TRTurkish (Turkey)t(16;21)(p11.2;q22.3)(FUS,ERG) füzyon transkript:Sç:Zmlı:Kan/Dk:Srl:Molgen
zh-CNChinese (China)t(16;21)(p11.2;q22.3)(FUS,ERG) 融合转录物:任意型:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: TLS 任意;任意的;人工型 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 时刻;随机;随意;瞬间 易位(16;21)(p11.2;q22.3)(FUS,ERG) 未作说明的组织;组织;组织 & 涂片 脂肪肉瘤之中的易位 脂肪肉瘤之中的易位（Translocation in liposarcoma，Translocated in liposarcoma，TLS） 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=70287-8