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Term Description

This term is used to identify a leukemia causing gene deletion at 1p32 resulting in a gene fusion between STIL and TAL1 where the STIL promoter controls TAL1. The term was created for (but not limited to) DNA Technology's HemaVision HV01-28N kit, a qualitative in vitro diagnostic test for 28 leukemia causing chromosomal alterations including more than 80 breakpoints plus associated mRNA splice variants. Reverse transcription followed by multiplex nested polymerase chain reactions (RT-PCR) and agarose gel electrophoresis are used to identify gene fusions caused by chromosomal translocations, gene deletions or inversions. Testing information is useful for predicting development of the disease and selection of treatment.

LOINC Names Get Info

Fully-Specified Name
Del(1)(p32p32)(STIL,TAL1) fusion transcript:PrThr:Pt:Bld/Tiss:Ord:Molgen
Long Common Name
Del(1)(p32p32)(STIL,TAL1) fusion transcript [Presence] in Blood or Tissue by Molecular genetics method
Short Name
Del(1p32)(STIL,TAL1) Bld/T Ql
Display Name
Del(1)(p32p32)(STIL,TAL1) fusion transcript Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
Del(1)(p32p32)(STIL,TAL1) fusion transcript analysis, Blood or tissue specimen

Part Model Get Info

  • Component
    Del(1)(p32p32)(STIL,TAL1) fusion transcript
    LP228263-2
    • Analyte
      Del(1)(p32p32)(STIL,TAL1) fusion transcript
      LP228263-2
      • Component Numerator
        Del(1)(p32p32)(STIL,TAL1) fusion transcript
        LP228263-2
        • Component Numerator Core
          Del(1)(p32p32)(STIL,TAL1)
          LP146082-5
        • Component Numerator Core Suffix
          fusion transcript
          LP150217-0
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Molgen
    LP6404-0

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MOLPATH.DEL
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.56 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
72103-5Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Fúzní transkript del(1)(p32p32)(STIL,TAL1):Přítomnost nebo práh:Časový bod:Krev/tkáň:Ordinální:Molekulární genetika
de-ATGerman (Austria)Synonyms: STIL-TAL1 Deletion (1) (p32p32)
el-GRGreek (Greece)Del(1)(p32p32)(STIL,TAL1) μεταγραφή συγχώνευσης:PrThr:Pt:Αίμα/Ιστός:Ord:Μοριακή γενετική
Synonyms: Del(1)(p32p32)(STIL,TAL1) MOLPATH MOLPATH.DEL Ord PrThr Pt Αίμα Αίμα/Ιστός Ιστός μεταγραφή συγχώνευσης Μοριακή γενετική
es-ESSpanish (Spain)Del(1)(p32p32)(STIL,TAL1) Tránscritos de fusión:PrThr:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MXSpanish (Mexico)Transcripción de fusión Del (1) (p32p32) (STIL, TAL1):Presencia o umbral:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-CAFrench (Canada)Del(1)(p32p32)(STIL,TAL1) transcrit de fusion:Présence-Seuil:Temps ponctuel:Sang/Tissu:Ordinal:Molgen
fr-FRFrench (France)Del(1)(p32p32)(STIL,TAL1) transcript de fusion:Présence/Seuil:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-ITItalian (Italy)del(1)(p32p32)(STIL,TAL1), trascritto di fusione:PrThr:Pt:Sangue/Tess:Ord:Molgen
Synonyms: delezione (1)(p32p32)(STIL,TAL1) Delezione genetica Genetica molecolare Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NLDutch (Netherlands)del(1)(p32p32)(STIL,TAL1) fusietranscript:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: molgen
pl-PLPolish (Poland)Del(1)(p32p32)(STIL,TAL1) transkrypt fuzyjny:granica wykrywalności:punkt w czasie:krew lub tkanka:uporządkowany:genetyka molekularna
Synonyms: Delecja(1)(p32p32) obejmującą geny STIL i TAL1 diagnostyka molekularna
ru-RURussian (Russian Federation)Del(1)(p32p32)(STIL,TAL1) слияния транскрипт:PrThr:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TRTurkish (Turkey)del(1)(p32p32)(STIL,TAL1) füzyon transkript:MevcEşik:Zmlı:Kan/Dk:Srl:Molgen
Synonyms: Mevcut
zh-CNChinese (China)del(1)(p32p32)(STIL,TAL1) 融合转录物:存在情况或阈值:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: Ⅰ I 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因缺失;分子病理学.缺失;分子病理学试验.基因缺失;分子病理学试验.缺失;分子病理学试验类.缺失;基因缺失;缺失 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 基因缺失(1)(p32p32)(STIL,TAL1);基因删除(1)(p32p32)(STIL,TAL1);基因敲除(1)(p32p32)(STIL,TAL1) 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=70289-4