Version 2.78

Part Descriptions

LP16182-5   Ofloxacin
Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. The original brand, Floxin, has been discontinued by the manufacturer in the United States in 2009, though generic equivalents continue to be available.

Oral and I.V. Floxin is not licensed by the FDA for use in children due to the risk of serious reversible and irreversible injury to the musculoskeletal system. Ofloxacin (and its derivatives) has also been associated with a few isolated reports of unexplained pediatric fatalities. Children (those under 18) are also at an increased risk of bone, joint, or tendon toxicities.

In the adult population ofloxacin is limited to the treatment of proven serious and life threatening bacterial infections such as:
Acute bacterial exacerbations of chronic bronchitis
Community-acquired pneumonia
Uncomplicated skin and skin structure infections
Nongonococcal urethritis and cervicitis
Mixed Infections of the urethra and cervix
Acute pelvic inflammatory disease
Uncomplicated cystitis
Complicated urinary tract infections
Prostatitis
Acute, uncomplicated urethral and cervical gonorrhea
Mycobacterial infections Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Ofloxacin (Wikipedia)

LP16182-5   Ofloxacin
A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION. Source: National Library of Medicine, MeSH 2006

LP6300-0   Gradient strip
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ofloxacin
Property
Susc
Time
Pt
System
Isolate
Scale
OrdQn
Method
Gradient strip

Additional Names

Short Name
Ofloxacin Islt Grad strip
Display Name
Ofloxacin Strip [Susc]
Consumer Name Alpha Get Info
Susceptibility to Ofloxacin

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 1.0h(2)
Last Updated
Version 2.56
Change Reason
Feb 2016-removed "E-test" from the short and long names because the "ETEST" name is trademarked
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
49589-5 Bacterial susceptibility panel by Gradient strip

Member of these Groups Get Info

LOINC Group Group Name
LG41088-2 OfloxacinSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Ofloxacin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Gradientenstreifen
es-AR Spanish (Argentina) ofloxacina:susceptibilidad:punto en el tiempo:cepa clínica:ordinal o cuantitativo:tirilla reactiva con gradiente
es-ES Spanish (Spain) Ofloxacina:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Tira de gradiente (E-prueba)
es-MX Spanish (Mexico) Ofloxacina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Tira de degradado
et-EE Estonian (Estonia) Ofloksatsiin:Susc:Pt:Is:OrdQn:E-test
Synonyms: Isolaat Juhuslik Tundlikkus
fr-CA French (Canada) Ofloxacine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Bâtonnet gradué
fr-FR French (France) Ofloxacine:Sensibilité:Ponctuel:Isolat:Alphanumérique:Bandelette graduée
fr-BE French (Belgium) Ofloxacine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Bâtonnet gradué
Synonyms: Tigette graduée
it-IT Italian (Italy) Ofloxacina:Susc:Pt:Isolato:OrdQn:Gradiente striscia
Synonyms: Gradiente striscia (E-test) Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
ko-KR Korean (Korea, Republic Of) 오플록사신:감수성:검사시점:분리주:정량 or 순위척도:그래디언 띠
nl-NL Dutch (Netherlands) ofloxacine:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:gradiëntstrip
pt-BR Portuguese (Brazil) Ofloxacina:Susc:Pt:Isolado:OrdQn:Fitas gradiente
Synonyms: Floxin; Susceptibility; Susceptibilty; Sus; Suscept; Susceptibilities; Point in time; Random; Islt; Isol; E-test; E-strip; Etest; Estrip; E-test; ANTIBIOTIC SUSCEPTIBILITIES
ru-RU Russian (Russian Federation) Офлоксацин:Чув:ТчкВрм:Изолят:ПорКол:Градиентная полоска
Synonyms: Градиентная полоска (Е-тест) Порядковый или Количественный Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Oflokzasin:Duyr:Zmlı:İzolat:SrlKant:Gradiyent çubuğu
zh-CN Chinese (China) 氧氟沙星:抗生素敏感性:时间点:分离株:定量型或序数型:梯度胶条法
Synonyms: E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条 分离物;分离菌;分离菌株;隔离种群 吡啶羧酶 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=7038-3