Version 2.77

Term Description

Cold agglutinins are usually determined at refrigerator temperatures (4 degrees C). In positive cases, surgeons may request testing at additional temperatures, including 18 degrees C, room temperature (22 degrees C), and 28 degrees C, to determine how cold the patient's body temperature can be dropped during surgery. In cardiovascular surgery, the heart is cooled to 25°C to slow down metabolic processes. Since the blood of patients with a history of cold antibodies or cold hemagglutinin disease (such as Raynaud's) is likely to contain cold antibodies, such as anti-M, anti-I and anti-I, testing at various temperatures is performed in order to prevent an acute hemolytic episode.
Source: Regenstrief LOINC

Part Descriptions

LP16679-0   Cold agglutinin
A cold agglutinin is an autoimmune disease in which the body produces antibodies against red blood cells, causing the cells to agglutinate (clump together). These antibodies are usually IgM. The primary form of cold agglutinin disease is idiopathic. In other cases, the disease is a result of an underlying condition. Cold aggulitinin disease is known to occur in adults with a lymphoproliferative disease, such as lymphoma and chronic lymphoid leukemia, and in children with infections such as Mycoplasma pneumonia, mononucleosis, and HIV. Cold agglutinins affect many blood tests, such as red blood cell count, and by default, the mean corpuscular hemoglobin and mean corpuscular volume. If these indices are very high, a technologist should suspect a cold agglutinin. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Cold agglutinin (Wikipedia)

LP16679-0   Cold agglutinin
Red cell antibodies that react more strongly at temperatures below 37 deg C. Source: Regenstrief Institute

Fully-Specified Name

Component
Cold agglutinin
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
18 deg C incubation

Additional Names

Short Name
CA Ser Ql 18 deg C inc
Display Name
Cold agglutinin 18 degree C incubation Ql (S)
Consumer Name Alpha Get Info
Cold Agglutinin, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Crioaglutininas:PrThr:Punto temporal:Suero:Ord:18 ºC de incubación
es-MX Spanish (Mexico) Aglutinina fría:Presencia o umbral:Punto temporal:Suero:Ordinal:Incubación a 18 grados C
fr-CA French (Canada) Agglutinine froide:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Incubation @ 18 C
fr-FR French (France) Agglutinines froides:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Incubation à 18°C
it-IT Italian (Italy) Agglutinina a freddo:PrThr:Pt:Siero:Ord:Incubazione a 18° C
Synonyms: Incubazione a 18 gradi C Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) koude agglutinatie:aanwezigheid:moment:serum:ordinaal:18 graden C-incubatie
pt-BR Portuguese (Brazil) Crio-aglutininas::Pt:Soro:Ord:18 deg C incubação
tr-TR Turkish (Turkey) Soğuk aglutinin:MevcEşik:Zmlı:Ser:Srl:18 C derc inkübasyon
Synonyms: Mevcut
zh-CN Chinese (China) 冷凝集素:存在情况或阈值:时间点:血清:序数型:18℃孵育
Synonyms: 18℃温育;18度孵育;18度温育;18摄氏度孵育;18摄氏度温育 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 保温 冷凝素;冷凝集素滴定;冷凝集素滴定试验;寒冷凝集素;红细胞抗体可在低于37摄氏度时发生更为强烈的反应。 培育 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 孵化 孵育方法 孵育类实验室方法 孵育类方法 孵育类检验方法 时刻;随机;随意;瞬间 温育 温育法 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

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