Version 2.80

Term Description

This test is used in the work up and management of hemochromatosis. Submitter's laboratory uses the method of MALDI-TOF with reference values recalculated from an ELISA method (see www.hepcidinanalysis.com).

Part Description

LP149244-8   Hepcidin 25 peptide
Hepcidin is a peptide hormone primarily synthesized in the liver and essential in regulating dietary iron absorption and distribution. Hepcidin lowers iron concentrations by counteracting the function of ferroportin, a major cellular iron exporter. Hepcidin forms include preprohormone (84 amino acids), prohormone (60 amino acids), and hormone (25 amino acids). Twenty- and 22-amino acid forms of Hepcidin also exist in the urine. The 25 amino acid form is referred to as the "bioactive" hepcidin since it can block the iron transporter ferroportin. The N terminal region is required for function and deletion of 5 N-terminal peptides results in a loss of function. Deficiency in hepcidin-25 concentration is associated with iron loading in hereditary hemochromatosis and thalassemia's. Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Regenstrief LOINC Information on reference values for Hepcidin 25 amnio acid analysis. Hepcidin Analysis- Reference Values

Fully-Specified Name

Component
Hepcidin 25 peptide
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Hepcidin 25 amino acid peptide [Moles/volume] in Serum or Plasma
Short Name
Hepcidin-25 SerPl-sCnc
Display Name
Hepcidin 25 amino acid peptide [Moles/Vol]
Consumer Name Alpha Get Info
Hepcidin 25 amino acid peptide, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Hepcidin-25
el-GR Greek (Greece) Πεπτίδιο εψιδίνη 25:SCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: SCnc Πεπτίδιο εψιδίνη 25
es-ES Spanish (Spain) Hepcidina péptido 25:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Péptido de hepcidina 25:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FR French (France) Hepcidine 1-25:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Epdicina 25, peptide:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Sostanza Peptide epdicina a 25 aminoacidi Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) hepcidine-25-peptide:mol/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Hepcidin 25 peptídeo::Pt:Soro/Plas:Qn:
ru-RU Russian (Russian Federation) Гепсидин 25 пептид:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Hepsidin 25 peptid:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 铁调素 25 肽:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 缩氨酸 肝脏表达抗菌肽;Liver-Expressed Antimicrobial Peptide;LEAP-1;Hepcidin-25;铁调素-25;铁调素 25 氨基酸肽;铁调节蛋白 25;调节血液铁离子浓度的关键因子;炎症和血浆铁离子过多时增多;主要在肝脏内表达;属于脊椎动物家族中新的抗菌小肽;含有8个半胱氨酸残基和4个二硫键;具有显著的抗细菌和抗真菌活性;抗菌肽;Antibacterial Peptides;AMP;抗微生物肽;肽抗生素;鐵調素;铁调素 血清或血浆

Example Units

Unit Source
nmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=71386-7