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Term Description

The fraction of vitamin B12 bound to transcobalamin II (TC-II), normally <30% of the total, is considered the "active" fraction available to cells. There have been claims in the literature that measurement of specifically the "active" fraction is an earlier indicator of deficiency, although as of 2011 this claim is reported to be controversial (Am J Clin Nutr. 2011 Jul;94(1):348S-358S. Epub 2011 May 18).

Part Description

LP156140-8   Holo-transcobalamin II
Vitamin B12 (cobalamin) is bound to 2 proteins in plasma, transcobalamin I (TC-1, sometimes called haptocorrin) and transcobalamin II (TC-II, called transcobalamin by those who use the term haptocorrin for transcobalamin I). TC-II saturated with vitamin B12 is known as holo-transcobalamin II (holo-TC-II) or "active" vitamin B12, which can be delivered into all DNA-synthesizing cells. Vitamin B12 bound to TC-1 (hapatocorrin) is unavailable in our metabolism. Apo-transcobalamin I and II (apo-TC-II and apo-TC-II) are unsaturated with vitamin b12. They play a role in the enterohepatic (re)cycling of cobalamin and are measured to diagnose the cause of a deficiency in B12. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Holo-transcobalamin II:SCnc:Pt:Ser:Qn:
Long Common Name
Holo-transcobalamin II [Moles/volume] in Serum
Short Name
Holo-TC-II Ser-sCnc
Display Name
Holo-transcobalamin II (S) [Moles/Vol]
Consumer Name Alpha Get Info
Holo-transcobalamin II, Blood

Part Model Get Info

  • Component
    Holo-transcobalamin II
    LP156140-8
    • Analyte
      Holo-transcobalamin II
      LP156140-8
      • Component Numerator
        Holo-transcobalamin II
        LP156140-8
        • Component Numerator Core
          Holo-transcobalamin II
          LP156140-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.42 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)كامل الترانكوبالامين 2 في المصل ( بتقنية عدد المولات / الحجم )
cs-CZCzech (Czechia)Holo-transkobalamin II:Látková koncentrace:Časový bod:Sérum:Kvantitativní:
de-ATGerman (Austria)Synonyms: Holo-Transcobalamin II
de-DEGerman (Germany)Holo-Transcobalamin II:Stoffmengenkonzentration:Zeitpunkt:Serum:Quantitativ:
el-GRGreek (Greece)Ολοτρανσκοβαλαμίνη ΙΙ:SCnc:Pt:Ορός:Qn:
Synonyms: CHEM Pt Qn SCnc Ολοτρανσκοβαλαμίνη ΙΙ Ορός Τρανσκοβαλαμίνη Τρανσκοβαλαμίνη ΙΙ
es-ESSpanish (Spain)Holo-transcobalamina II:Concentración de sustancia:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Holo-transcobalamina II:Concentración de sustancias:Punto temporal:Suero:Cuantitativo:
fr-FRFrench (France)Holo-transcobalamine II:Moles/Volume:Ponctuel:Sérum:Numérique:
it-ITItalian (Italy)Olotranscobalamina II:SCnc:Pt:Siero:Qn:
Synonyms: Chimica Concentrazione di Sostanza Punto nel tempo (episodio) Siero TC TC II
nl-NLDutch (Netherlands)holo-transcobalamine II:mol/volume:moment:serum:kwantitatief:
ru-RURussian (Russian Federation)Холо-транскобаламин II:МолКонц:ТчкВрм:Сыв:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Сыворотка Точка во времени;Момент Холотранскобаламин II
tr-TRTurkish (Turkey)Holo-transkobalamin II:SubKons:Zmlı:Ser:Kant:
zh-CNChinese (China)Holo-运钴胺素蛋白 II:物质的量浓度:时间点:血清:定量型:
Synonyms: TC TC-2;TC-II;运钴胺素蛋白 2 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 全-运钴胺素蛋白 II;完整-运钴胺素蛋白 II 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间

Example Units

UnitSource
pmol/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72160-5