Version 2.78

Term Description

An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
Source: Regenstrief LOINC

Part Description

LP19835-5   t(12;21)(p13;q22.3)(ETV6,RUNX1)
The chromosomal translocation t(12;21)(p13;q22) results in a fused transcript between ETV6-RUNX1 (TEL-AML1) genes and is the most common translocation in B cell childhood acute lymphoblastic leukemia (ALL), accounting for 25% of childhood ALL. Molecular and cytogenetic techniques such as real-time PCR and FISH are used to detect the ETV6-RUNX1 fused transcripts. Source: Regenstrief LOINC

Fully-Specified Name

Component
t(12;21)(p13;q22.3)(ETV6,RUNX1) fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bone mar
Scale
Qn
Method
Molgen

Additional Names

Long Common Name
t(12;21)(p13;q22.3)(ETV6,RUNX1) fusion transcript/control transcript [# Ratio] in Bone marrow by Molecular genetics method
Short Name
t(12;21)(ETV6,RUNX1)/control Mar
Display Name
t(12;21)(p13;q22.3)(ETV6,RUNX1) fusion transcript/control transcript Molgen (BM) [# ratio]
Consumer Name Alpha Get Info
t(12;21)(p13;q22.3)(ETV6,RUNX1)/control Transcript, Bone marrow

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
18933

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(12;21)(p13;q22.3)(ETV6,RUNX1) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Médula ósea:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (12; 21) (p13; q22.3) (ETV6, RUNX1) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Médula ósea:Cuantitativo:Genética molecular
fr-FR French (France) t(12;21)(p13;q22.3)(ETV6,RUNX1) transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Moelle osseuse:Numérique:Biologie moléculaire
fr-CA French (Canada) t(12;21)(p13;q22.3)(ETV6,RUNX1) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Moelle osseuse:Quantitatif:Molgen
it-IT Italian (Italy) t(12;21)(p13;q22.3)(ETV6,RUNX1), trascritto di fusione/trascritto di controllo:NRto:Pt:Mid oss:Qn:Molgen
Synonyms: Genetica molecolare Midollo osseo Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Traslocazione genetica
nl-NL Dutch (Netherlands) t(12;21)(p13;q22.3)(ETV6,RUNX1) fusietranscript/controle transcript:aantalsverhouding:moment:beenmerg:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(12;21)(p13;q22.3)(ETV6,RUNX1) transcrição de fusão/controle de transcrição::Pt:MedOssea:Qn:Genética molecular
ru-RU Russian (Russian Federation) t(12;21)(p13;q22.3)(ETV6,RUNX1) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Костный мозг:Колич:МолГен
Synonyms: Количественное отношение Количественный Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(12;21)(p13;q22.3)(ETV6,RUNX1) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kem il:Kant:Molgen
zh-CN Chinese (China) t(12;21)(p13;q22.3)(ETV6,RUNX1) 融合转录物/对照转录物:计数型比率:时间点:骨髓:定量型:分子遗传学类实验室方法
Synonyms: AML1 ETS 变体基因 6 ETS 差异基因 6 ETS 突变体基因 6 ETS 突变基因 6 ETS 突变基因 6（ets variant gene 6，ETV6） T(12,21)(ETV6,CBFA2) 基因易位;T(12,21)(ETV6,CBFA2) 易位 TEL TEL 癌基因 TEL 癌基因（Tel oncogene） TEL 致癌基因 TEL1 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 急性髓性白血病 1 急性髓系白细胞 1 急性髓系白细胞 1（Acute myeloid leukemia 1） 急性髓细胞白血病 1 时刻;随机;随意;瞬间 易位 ETS 白血病 易位 ETS 白血病（Translocation ets leukemia，TEL） 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 骨骼;骨头 髓

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72217-3