72274-4

t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

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Part Description

LP150268-3 t(15;17)(q24.1;q21.1)(PML,RARA)
The fusion of promyelocytic leukemia (PML, chromosome 15q24.1) and retinoic acid receptor alpha (RARA, chromosome 17q21.1) genes occurs due to a chromosomal translocation. The fused genes can be detected by various molecular techniques, including FISH and real-time quantitative polymerase chain reaction (RT-qPCR). The test is used to diagnose Acute Promyelocytic Leukemia (APL), detect residual or recurrent APL, and to monitor PML-RARA levels in patients with APL. The assay can be done on whole blood (plasma or cell-based) and bone marrow. Long, variant and/or short isoforms of PML-RARA fusion transcripts may be identified. The ratio of PML-RARA fusion transcript to a control gene (e.g. ABL1) may be reported for positive samples. Source: Regenstrief LOINC

Fully-Specified Name

Component: t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript
Property: NRto
Time: Pt
System: Bld/Tiss
Scale: Qn
Method: Molgen

Additional Names

Long Common Name: t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method
Short Name: t(15;17)(PML,RARA)/control Bld/T
Display Name: t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info: t(15;17)(q24.1;q21.1)(PML,RARA)/control Transcript, Blood or tissue specimen

Basic Attributes

Class: MOLPATH.TRNLOC
Type: Laboratory
First Released: Version 2.42
Last Updated: Version 2.42
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
72104-3	Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	t(15;17)(q24.1;q21.1)(PML,RARA) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	t (15; 17) (q24.1; q21.1) (PML, RARA) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR	French (France)	t(15;17)(q24.1;q21.1)(PML,RARA) transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA	French (Canada)	t(15;17)(q24.1;q21.1)(PML,RARA) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT	Italian (Italy)	t(15;17)(q24.1;q21.1)(PML,RARA), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL	Dutch (Netherlands)	t(15;17)(q24.1;q21.1)(PML,RARA) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek Synonyms: molgen
pt-BR	Portuguese (Brazil)	t(15;17)(q24.1;q21.1)(PML,RARA) transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU	Russian (Russian Federation)	t(15;17)(q24.1;q21.1)(PML,RARA) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Промиелоцитарный лейкоз Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR	Turkish (Turkey)	t(15;17)(q24.1;q21.1)(PML,RARA) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN	Chinese (China)	t(15;17)(q24.1;q21.1)(PML,RARA) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法 Synonyms: MYL NR1B1 PML-1 PML-2 PML-3 PML-3B PML-X RAR alpha 型 RAR α型 RARalpha RARα 全血或组织;血液/组织;血液或组织分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应前髓细胞白血病可用数量表示的;定量性;数值型;数量型;连续数值型标尺同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本早幼粒细胞性白血病早幼粒细胞白血病早幼粒细胞白血病（Promyelocytic leukemia，PML）时刻;随机;随意;瞬间易位(15;17)(q24.1;q21.1)(PML,RARA) 未作说明的组织;组织;组织 & 涂片融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录血;血液视黄酸受体 alpha 视黄酸受体 alpha（Retinoic acid receptor alpha，RARA，RARalpha，RAR alpha）视黄酸受体 α

Example Units

Unit	Source
{ratio}	Example UCUM Units

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.