LP150268-3
t(15;17)(q24.1;q21.1)(PML,RARA)
Active
Description
The fusion of promyelocytic leukemia (PML, chromosome 15q24.1) and retinoic acid receptor alpha (RARA, chromosome 17q21.1) genes occurs due to a chromosomal translocation. The fused genes can be detected by various molecular techniques, including FISH and real-time quantitative polymerase chain reaction (RT-qPCR). The test is used to diagnose Acute Promyelocytic Leukemia (APL), detect residual or recurrent APL, and to monitor PML-RARA levels in patients with APL. The assay can be done on whole blood (plasma or cell-based) and bone marrow. Long, variant and/or short isoforms of PML-RARA fusion transcripts may be identified. The ratio of PML-RARA fusion transcript to a control gene (e.g. ABL1) may be reported for positive samples. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- t(15;17)(q24.1;q21.1)(PML,RARA)
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2012-05-21
- Construct for LOINC Short Name
- t(15;17)(PML,RARA)
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | t(15; Synonyms: 易位(15; |
| fr-CA | French (Canada) | t(15; |
| es-ES | Spanish (Spain) | t(15; |
| it-IT | Italian (Italy) | t(15; |
| tr-TR | Turkish (Turkey) | t(15; |
| ru-RU | Russian (Russian Federation) | t(15; |
| nl-NL | Dutch (Netherlands) | t(15; |
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