72313-0

t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

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Term Description

A translocation involving chromosomes 4 and 11, t(4;11)(q21.3;q23), results in a fused transcript between AFF1 and MLL genes. The AFF1-MLL fusion gene is associated with childhood and adult acute lymphoblastic leukemia (ALL) as well as infant acute leukemia. This code is based on, but not limited to, Ispogen's FusionQuant® kit, which uses real-time Quantitative RQ-PCR to quantify the expression level of specific AFF1-MLL fusion transcripts relative to a control gene transcript (e.g. ABL1). Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.

LOINC Names Get Info

Fully-Specified Name: t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript:NRto:Pt:Bld/Tiss:Qn:Molgen
Long Common Name: t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method
Short Name: t(4;11)(AFF1,MLL)/control Bld/T
Display Name: t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info: t(4;11)(q21.3;q23)(AFF1,MLL)/control Transcript, Blood or tissue specimen

Part Model Get Info

Component
t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript
LP287175-6
- Analyte
  t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript
  LP287175-6
  - Component Numerator
    t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript
    LP229754-9
    - Component Numerator Core
      t(4;11)(q21.3;q23)(AFF1,MLL)
      LP19843-9
    - Component Numerator Core Suffix
      fusion transcript
      LP150217-0
  - Component Denominator
    control transcript
    LP150246-9
    - Component Denominator Core
      control transcript
      LP150246-9
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NRto
LP6840-5
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld/Tiss
LP7061-7
- System Core
  Bld/Tiss
  LP7061-7
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Molgen
LP6404-0

Basic Attributes

Class: MOLPATH.TRNLOC
Type: Laboratory
First Released: Version 2.42
Last Updated: Version 2.42 (MIN)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
72104-3	Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Fúzní transkript t(4;11)(q21.3;q23)(AFF1,MLL)/kontrolní transkript:Početní poměr:Časový bod:Krev/tkáň:Kvantitativní:Molekulární genetika
el-GR	Greek (Greece)	t(4;11)(q21.3;q23)(AFF1,MLL) μεταγραφή συγχώνευσης/μεταγραφή ελέγχου:NRto:Pt:Αίμα/Ιστός:Qn:Μοριακή γενετική Synonyms: MOLPATH MOLPATH.TRNLOC NRto Pt Qn t(4;11)(q21.3;q23)(AFF1,MLL) Αίμα Αίμα/Ιστός Ιστός μεταγραφή ελέγχου μεταγραφή συγχώνευσης Μοριακή γενετική
es-ES	Spanish (Spain)	t(4;11)(q21.3;q23)(AFF1,MLL) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	t (4; 11) (q21.3; q23) (AFF1, MLL) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR	French (France)	t(4;11)(q21.3;q23)(AFF1,MLL) transcript de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA	French (Canada)	t(4;11)(q21.3;q23)(AFF1,MLL) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT	Italian (Italy)	t(4,11)(q21.3,q23)(AFF1,MLL), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL	Dutch (Netherlands)	t(4;11)(q21.3;q23)(AFF1,MLL) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek Synonyms: molgen
pl-PL	Polish (Poland)	t(4;11)(q21.3;q23)(AFF1,MLL) transkrypt fuzyjny/transkrypt kontrolny:współczynnik liczbowy:punkt w czasie:krew lub tkanka:ilościowy:genetyka molekularna Synonyms: diagnostyka molekularna
ru-RU	Russian (Russian Federation)	t(4;11)(q21.3;q23)(AFF1,MLL) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR	Turkish (Turkey)	t(4;11)(q21.3;q23)(AFF1,MLL) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN	Chinese (China)	t(4;11)(q21.3;q23)(AFF1,MLL) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法 Synonyms: AF4 ALL1 ALL-1 FEL HRX HTRX HTRX1 T(4,11)(MLLT2,MLL) 基因易位;T(4,11)(MLLT2,MLL) 易位 TRX1 三胸同源基因三胸同源基因（Homolog of trithorax）三胸同源物全血或组织;血液/组织;血液或组织分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应可用数量表示的;定量性;数值型;数量型;连续数值型标尺同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录血;血液髓/淋巴混合系白血病 (三胸(果蝇)) 髓/淋巴混合系白血病 (三胸(果蝇)同源基因) 髓/淋系或混合型白血病 (三胸(果蝇)) 髓/淋系或混合型白血病 (三胸(果蝇)同源基因) 髓/淋系或混合性白血病 (三胸(果蝇)) 髓/淋系或混合性白血病 (三胸(果蝇)同源基因) 髓/淋系或混合系白血病 (三胸(果蝇)) 髓/淋系或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋巴样或混合型白血病 (三胸(果蝇)) 髓系/淋巴样或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋巴样或混合性白血病 (三胸(果蝇)) 髓系/淋巴样或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋巴样或混合系白血病 (三胸(果蝇)) 髓系/淋巴样或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋巴系或混合型白血病 (三胸(果蝇)) 髓系/淋巴系或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋巴系或混合性白血病 (三胸(果蝇)) 髓系/淋巴系或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋巴系或混合系白血病 (三胸(果蝇)) 髓系/淋巴系或混合系白血病 (三胸(果蝇))（Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila))）髓系/淋巴系或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋巴系或混合系白血病 (三胸(果蝇)同源基因) （Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog)）髓系/淋巴细胞性或混合型白血病 (三胸(果蝇)) 髓系/淋巴细胞性或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞性或混合性白血病 (三胸(果蝇)) 髓系/淋巴细胞性或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞性或混合系白血病 (三胸(果蝇)) 髓系/淋巴细胞性或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞或混合型白血病 (三胸(果蝇)) 髓系/淋巴细胞或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞或混合性白血病 (三胸(果蝇)) 髓系/淋巴细胞或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞或混合系白血病 (三胸(果蝇)) 髓系/淋巴细胞或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋系或混合型白血病 (三胸(果蝇)) 髓系/淋系或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋系或混合性白血病 (三胸(果蝇)) 髓系/淋系或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋系或混合系白血病 (三胸(果蝇)) 髓系/淋系或混合系白血病 (三胸(果蝇)同源基因)

Example Units

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%	Example UCUM Units

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