72320-5

Mitochondria M2-3E IgG Ab [Presence] in Serum by Immunoassay

Active

Term Description

Autoantibodies directed against a recombinant mitochondrial fusion protein, M2-3E (BPO), can be detected by enzyme immunoassays. Results may be interpreted by humans or automated methods and used for the diagnosis of primary biliary cirrhosis. This code was created for, but not limited to, the detection of M2-3E autoantibodies by Euroimmun's EUROLINE Profile Autoimmune Liver Diseases (IgG) test kit.

Part Description

LP157237-1 Mitochondria M2-3E
M2-3E (BPO) antigen is a recombinant fusion protein that is made up of the E2 subunits of the branched-chain 2-oxoacid dehydrogenase (BCOADH), pyruvate dehydrogenase (PDH) and 2-oxoglutarate dehydrogenase (OGDH). The presence of anti-mitochondrial antibodies (AMA) against M2-3E antigens is used for the diagnosis of primary biliary liver cirrhosis (PBC), an immune-mediated chronic inflammatory liver disease of unknown cause. Approximately 86% of patients with PBC have M2-3E autoantibodies. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Mitochondria M2-3E Ab.IgG:PrThr:Pt:Ser:Ord:IA
Long Common Name: Mitochondria M2-3E IgG Ab [Presence] in Serum by Immunoassay
Short Name: M2-3E IgG Ser Ql IA
Display Name: Mitochondria M2-3E IgG IA Ql (S)
Consumer Name Alpha Get Info: Mitochondria M2-3E IgG antibody, Blood

Part Model Get Info

Component
Mitochondria M2-3E Ab.IgG
LP157235-5
- Analyte
  Mitochondria M2-3E Ab.IgG
  LP157235-5
  - Component Numerator
    Mitochondria M2-3E Ab.IgG
    LP157235-5
    - Component Numerator Core
      Mitochondria M2-3E
      LP157237-1
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
IA
LP217197-5

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.42
Last Updated: Version 2.56 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
85092-5	Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Mitochondrie M2-3E IgG:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Imunoanalýza
el-GR	Greek (Greece)	Μιτοχόνδρια M2-3E Αντισώματα IgG:PrThr:Pt:Ορός:Ord:IA Synonyms: IA Ord PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Μιτοχόνδρια Μιτοχόνδρια M2 Μιτοχόνδρια M2-3E Ορός
es-ES	Spanish (Spain)	Mitocondria M2-3E IgG:PrThr:Punto temporal:Suero:Ord:IA
es-MX	Spanish (Mexico)	Mitocondrias M2-3E Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunoensayo
fr-FR	French (France)	Mitochondries M2-3E Ac IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
it-IT	Italian (Italy)	Mitocondri M2-3E Ab.IgG:PrThr:Pt:Siero:Ord:IA Synonyms: anticorpi IgG anticorpo Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	mitochondriaal M2-3E As.IgG:aanwezigheid:moment:serum:ordinaal:immunoassay Synonyms: antistof; antilichaam IA
pt-BR	Portuguese (Brazil)	Mitocondria M2-3E Ac.IgG:Limiar:Pt:Soro:Ord:Imunoensaio
ru-RU	Russian (Russian Federation)	Митохондрия M2-3E Ат.IgG:PrThr:ТчкВрм:Сыв:Пор:IA Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Mitokondri M2-3E Ab.IgG:MevcEşik:Zmlı:Ser:Srl:İA Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut
zh-CN	Chinese (China)	线粒体 M2-3E 抗体.IgG:存在情况或阈值:时间点:血清:序数型:免疫测定法 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间线粒体特异性;线粒体的血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类重组型线粒体融合蛋白 M2-3E (BPO)

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.