Version 2.80

Term Description

Apparent mineralocorticoid excess is a rare recessive genetic disease that is characterized by childhood onset of hypertension, hypokalemic alkalosis, and low plasma renin and aldosterone level. Hypertension is due to impaired conversion of cortisol to cortisone due to an inactive 11β-hydroxysteroid dehydrogenase. This condition may be diagnosed with elevated cortisol metabolite to cortisone metabolite ratios in urine or serum. It is recommended that cortisol/cortisone ratios (F/E) be tested in hypokalemic hypertension cases where aldosterone, deoxycorticosterone, and renin are all low. Elevated cortisol/cortisone ratios may be found in chronic renal failure, or excessive ingestion of glycyrrhetinic acid or derivatives, or in liver or bile-acid abnormalities.

Part Description

LP14161-1   Cortisol
Cortisol is a glucocorticoid produced in the adrenal cortex. A synthetic version of this same chemical is called hydrocortisone and manufactured as medication. Cortisol is not to be confused with cortisone, a closely related compound with much less (PubChem calls it "inactive") biologic activity. Cortisone is also offered as a drug, and it is converted to cortisol (the active form) in the liver. They both have a circadian rhythm with peak in the AM (around 8AM) and trough in the evening (around midnight), but this shifts according to sleep habits (work shifts). The morning measurement, which should be high, is most useful for diagnosing Addison's disease (too little cortisol) and the evening measurement, which should be low, is the most useful for diagnosing Cushing's disease (too much cortisol). Salivary cortisol may be a more sensitive measure than serum or plasma. Source: Regenstrief Help

Fully-Specified Name

Component
Cortisol/Cortisone
Property
MRto
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Cortisol/Cortisone [Mass Ratio] in Serum or Plasma
Short Name
Cortis/Cortisone SerPl
Display Name
Cortisol/Cortisone [Mass ratio]
Consumer Name Alpha Get Info
Cortisol/Cortisone, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Observation
Common Test Rank Get Info
16097

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κορτιζόλη/Κορτιζόνη:MRto:Pt:Ορός/Πλάσμα:Qn:
Synonyms: MRto Κορτιζόλη Κορτιζόνη
es-ES Spanish (Spain) Cortisol/Cortisona:Relacion de Masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Cortisol / Cortisona:Relación de masa:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FR French (France) Cortisol/cortisone:Masse ratio:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Cortisolo/Cortisone:MRto:Pt:Siero/Plasma:Qn:
Synonyms: Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Rapporto di Massa Siero Siero o Plasma
nl-NL Dutch (Netherlands) cortisol/cortison:massaverhouding:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Cortisol/Cortisona::Pt:Soro/Plas:Qn:
ru-RU Russian (Russian Federation) Кортизол/Кортизон:МассОтн:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Масс отношение Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Kortizol/Kortizon:KütlOr:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 皮质醇/可的松:质量比率:时间点:血清/血浆:定量型:
Synonyms: 17羟11脱氢皮甾酮;17-羟-11-脱氢皮甾酮;化合物 E 17-羟皮质甾酮;17-羟皮质酮;化合物 F;可的索;氢化可的松;皮质甾醇;考的索 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 来自于同一体系的两种分析物的质量之比;质量比 毒品 毒品类 考的松;皮质素;考地松;醋酸副肾皮质素;醋酸肾上腺皮质素;醋酸皮质酮;皮质酮;可体松;醋酸可的松;肾上腺皮质激素;17-羟-11脱氢皮质酮;17-羟-11脱氢皮质甾酮;肾上腺类皮质激素型药物 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72392-4