72489-8
Androstenedione [Moles/volume] in Saliva (oral fluid)
Active
Part Descriptions
LP14493-8 Androstenedione
Androstenedione (also known as 4-androstenedione) is a 19-carbon steroid hormone produced in the adrenal glands and the gonads as an intermediate step in the biochemical pathway that produces the androgen testosterone and the estrogens estrone and estradiol. It is the common precursor of male and female sex hormones. Some androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens. Androstenedione originates either from the conversion of dehydroepiandrosterone or from 17-hydroxyprogesterone. It is further converted to either testosterone or estrone. The production of adrenal androstenedione is governed by ACTH, while production of gonadal androstenedione is controled by gonadotropins. In premenopausal women the adrenal glands and ovaries each produce about half of the total androstendione (about 3 mgday).
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Source: Wikipedia, Androstenedione (Wikipedia)
LP14493-8 Androstenedione
Testing for androstenedione is used to diagnose viralizing syndromes including congenital adrenal hyperplasia, female virilization, hirsutism, polycystic ovarian disease, Stein-Levethal syndrome. and to detect abuse of anabolic steroids. It is also a drug- an anabolic steroid- used to enhance atheletic performance, but banned as an OTC drug by the FDA in 2004.
Source: Regenstrief Institute
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Androstenedione
- Property
- SCnc
- Time
- Pt
- System
- Saliva
- Scale
- Qn
- Method
Additional Names
- Short Name
- Androst Sal-sCnc
- Display Name
- Androstenedione (Sal) [Moles/Vol]
- Consumer Name Alpha Get Info
- Androstenedione, Saliva
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.42
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Androstenediona: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Androstenediona: |
et-EE | Estonian (Estonia) | Androsteendioon: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Sülg |
fr-CA | French (Canada) | Androstènedione: |
fr-FR | French (France) | Androstènedione: |
fr-BE | French (Belgium) | Androstènedione: |
it-IT | Italian (Italy) | Androstenedione: Synonyms: Chimica Concentrazione di Sostanza Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | androsteendion: |
pt-BR | Portuguese (Brazil) | Androstenediona: |
ru-RU | Russian (Russian Federation) | Андростендион: Synonyms: Количественный Молярность; |
tr-TR | Turkish (Turkey) | Androstenediyon: |
zh-CN | Chinese (China) | 雄烯二酮: Synonyms: Androst; |
Example Units
Unit | Source |
---|---|
pmol/L | Example UCUM Units |
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