Version 2.80

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus DNA
Property
LaCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
Probe.amp.tar

Additional Names

Long Common Name
Cytomegalovirus DNA [log units/volume] (viral load) in Serum or Plasma by NAA with probe detection
Short Name
CMV DNA SerPl NAA+probe-Log IU
Display Name
CMV DNA NAA+probe [Log units/Vol]
Consumer Name Alpha Get Info
Cytomegalovirus (CMV), Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73 (MAJ)
Change Reason
Release 2.73: SYSTEM: changed to fit like terms with serum and/or plasma;
Order vs. Observation
Both
Common Test Rank Get Info
1162

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cytomegalie-Virus DNA:Logarithmische Einheitenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
Synonyms: CMV
el-GR Greek (Greece) Κυτταρομεγαλοϊός DNA:LaCnc:Pt:Ορός/Πλάσμα:Qn:Ανιχνευτής.ενίσχυση.στόχου
Synonyms: DNA LaCnc Κυτταρομεγαλοϊός
es-ES Spanish (Spain) Citomegalovirus ADN:Concentración logarítmica:Punto temporal:Suero o Plasma:Qn:Sonda con amplificación dirigida
Synonyms: Cuantitativo
es-MX Spanish (Mexico) ADN de citomegalovirus:Concentración de unidades logarítmicas:Punto temporal:Plasma:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Cytomégalovirus, ADN:Concentration arbitraire exprimée en log:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec amplification de la cible
fr-FR French (France) Cytomégalovirus ADN:Log arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:PCR amplification de cible
fr-BE French (Belgium) Cytomégalovirus ADN:Concentration arbitraire exprimée en log:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec amplification de la cible
Synonyms: CMV Concentration Log
it-IT Italian (Italy) Citomegalovirus DNA:LaCnc:Pt:Siero/Plasma:Qn:Sonda.amp.tar
Synonyms: Concentrazione logaritmica Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) Cytomegalovirus DNA:logaritmische eenheid/volume:moment:serum of plasma:kwantitatief:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Citomegalovírus DNA::Pt:Plas:Qn:Sonda com limite de detecção da amplificação de alvo
ru-RU Russian (Russian Federation) Цитомегаловирус ДНК:LaCnc:ТчкВрм:Сыв/Плаз:Колич:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Количественный Концентрация в логарифмических единицах Плазма Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Cytomegalovirus DNA:LogKons:Zmlı:Ser/Plaz:Kant:Prob.amf.hdf
uk-UA Ukrainian (Ukraine) Цитомегаловірус ДНК:Log Довільна Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:Зонд-детекція. цільова аміпліфікація НК
Synonyms: 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; CMV; Cytomegalo virus; Cytomgal; Deoxyribonucleic acid; DNA NUCLEIC ACID PROBE; DNA probe; HHV-5; Human Herpesvirus-5; ID; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Log ACNC; Log IU; Microbiology; NAA+probe; NAAT; NASBA; Nucleic acid sequence based analysis; PCR; Pl; Plasma; Plsm; Point in time; Polymerase chain reaction; Probe amp; Probe with ampification; Probe with target amplification; QBR; QNT; Quan; Quant; Quantitative; Random; SDA; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Strand Displacement Amplification; TMA; Transcription mediated amplification; Viral load
zh-CN Chinese (China) 巨细胞病毒 DNA:对数型任意浓度:时间点:血清/血浆:定量型:探针法.基因扩增.靶向
Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 对数任意浓度 探针法.基因扩增.靶向 对数任意浓度 探针法.扩增.靶向 对数任意浓度;任意浓度之对数 对数型任意浓度 探针法.扩增.靶向 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 病毒负荷 病毒负荷量 病毒负载 病毒载量 病毒载量（Viral load） 经过扩增的 脱氧核糖核酸探针 血清或血浆

Example Units

Unit Source
{Log_IU}/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72494-8