LOINC
Version 2.67

72520-0FLT3 gene p.Asp835+Ile836 [Presence] in Blood or Tissue by Molecular genetics methodActive

Term Description

Point mutations and deletions of codons D835 and I836 within the second tyrosine kinase domain (protein activation loop) of the FLT3 gene are detected by molecular genetic methods (e.g. PCR-based assays). This code was created for, but not limited to Invivoscribe's LeukoStrat(tm) FLT3 Gel Detection Mutation Assay, which detects the presence or absence of either D835 or I836 mutations within the second TKD but does not identify specific TKD mutations. FLT3-TKD mutations occur in approximately 7% of patients with acute myelogenous leukemia (AML).
Source: Regenstrief LOINC

Fully-Specified Name

Component
FLT3 gene.p.Asp835+Ile836
Property
PrThr
Time
Pt
System
Bld/Tiss
Scale
Ord
Method
Molgen

Additional Names

Short Name
FLT3 p.D835+I836 Bld/T Ql
Display Name
FLT3 gene p.Asp835+Ile836 Molgen Ql (Bld/Tiss)

Basic Attributes

Class
MOLPATH.MUT
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.56
Change Reason
Changed Component name to align with the current HGVS recommendations to use the three letter codes for amnio acids. In the shortname, we kept the single letter codes.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
FLT3 基因.p.D835+I836:存在情况或阈值:时间点:全血/组织:序数型:分子遗传学类实验室方法
nl-NLDutch (NETHERLANDS)
FLT3-gen.p.D835+I836:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
fr-CAFrench (CANADA)
Gène FLT3.p.Asp835+Ile836:Présence-Seuil:Temps ponctuel:Sang/Tissu:Ordinal:Molgen
fr-FRFrench (FRANCE)
FLT3 gène p.Asp835+Ile836:Présence/Seuil:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
de-ATGerman (AUSTRIA)
FLT3 Genmutation (Asp835+Ile836)
it-ITItalian (ITALY)
FLT3, gene.p.Asp835+Ile836:PrThr:Pt:Sangue/Tess:Ord:Molgen
pt-BRPortuguese (BRAZIL)
ru-RURussian (RUSSIAN FEDERATION)
FLT3 ген.p.D835+I836:PrThr:ТчкВрм:Кр/Тк:Пор:МолГен
es-ESSpanish (SPAIN)
Gen FLT3 pD835+I836:PrThr:Punto temporal:Sangre o tejido:Ord:Genética molecular
tr-TRTurkish (TURKEY)
FLT3 geni.p.D835+I836:MevcEşik:Zmlı:Kan/Dk:Srl:Molgen

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72520-0