72612-5
ALPRAZolam [Presence] in Saliva (oral fluid)
Active
Part Descriptions
LP14981-2 ALPRAZolam
Alprazolam (brand name Xanax) is a short-acting anxiolytic of the benzodiazepine class of psychoactive drugs, used to treat anxiety and panic disorders. It works by binding to gamma aminobutyric acid (GABA) receptors in the brain to increase GABA-mediated synaptic inhibition. Alprazolam is also sometimes used to treat depression, fear of open spaces (agoraphobia), and premenstrual syndrome. Alprazolam can be habit-forming and some of the more serious potential side effects are: shortness of breath, seizures, hallucinating, severe skin rash, yellowing of the skin or eyes, depression, memory problems, confusion, problems with speech, unusual changes in behavior or mood, and suicidal thoughts.
Source: Regenstrief LOINC,
MedlinePlus: a684001
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- ALPRAZolam:
PrThr: Pt: Saliva: Ord: - Long Common Name
- ALPRAZolam [Presence] in Saliva (oral fluid)
- Short Name
- Alpraz Sal Ql
- Display Name
- ALPRAZolam Ql (Sal)
- Consumer Name Alpha Get Info
- ALPRAZolam, Saliva
Part Model Get Info
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 16216
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Alprazolam: |
| el-GR | Greek (Greece) | Αλπραζολάμη: Synonyms: DRUG/TOX Ord PrThr Pt Αλπραζολάμη Σίελος |
| es-ES | Spanish (Spain) | Alprazolam: |
| es-MX | Spanish (Mexico) | ALPRAZolam: |
| et-EE | Estonian (Estonia) | Alprasolaam: Synonyms: Järgarvuline Juhuslik Sülg |
| fr-CA | French (Canada) | ALPRAZolam: |
| fr-FR | French (France) | Alprazolam: |
| fr-BE | French (Belgium) | Alprazolam: |
| it-IT | Italian (Italy) | Alprazolam: Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | alprazolam: |
| pl-PL | Polish (Poland) | Alprazolam: |
| pt-BR | Portuguese (Brazil) | Alprazolam: |
| ru-RU | Russian (Russian Federation) | Алпразолам: Synonyms: Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | Alprazolam: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 阿普唑仑: Synonyms: 依次型; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Third Party Copyright
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://