Version 2.80

Part Descriptions

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Trough levels for therapeutic drug monitoring

LP21368-3   Sirolimus
Sirolimus, also known as rapamycin, is a macrolide compound that inhibits lymphocyte proliferation and is used as an immunosuppressant to prevent rejection in organ transplantation. It inhibits T-cell activation and proliferation by inhibiting the response to interleukin 2 (IL-2). Its mode of action differs from that of other immunosuppressants (SN Sehga, Clin Biochem, 31:335, 1998) most notably by not being a calcineurin inhibitor. Its inhibitory action is mediated via a cytosolic protein, FK-binding protein 12. Sirolimus is variably absorbed; levels need to monitored to achieve the therapeutic target while avoiding toxic levels. Sirolimus is marketed under the trade name Rapamune. Source: Regenstrief LOINC

Fully-Specified Name

Component
Sirolimus^trough
Property
MCnc
Time
Pt
System
Plas
Scale
Qn
Method

Additional Names

Long Common Name
Sirolimus [Mass/volume] in Plasma --trough
Short Name
Sirolimus Trough Plas-mCnc
Display Name
Sirolimus trough (P) [Mass/Vol]
Consumer Name Alpha Get Info
Sirolimus trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.42 (MIN)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Σιρόλιμους^ελάχιστα επίπεδα:MCnc:Pt:Πλάσμα:Qn:
Synonyms: MCnc Σιρόλιμους
es-ES Spanish (Spain) Sirolimus^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Sirolimus ^ a través:Concentración de masa:Punto temporal:Plasma:Cuantitativo:
et-EE Estonian (Estonia) Siroliimus^baas:MCnc:Pt:P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma
fr-CA French (Canada) Sirolimus^Creux:Concentration de masse:Temps ponctuel:Plasma:Quantitatif:
fr-FR French (France) Sirolimus taux résiduel:Masse/Volume:Ponctuel:Plasma:Numérique:
fr-BE French (Belgium) Sirolimus^Creux:Concentration de masse:Temps ponctuel:Plasma:Quantitatif:
Synonyms: Minimum, nadir
it-IT Italian (Italy) Sirolimus^valore minimo:MCnc:Pt:Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) valore minimo TDM
nl-NL Dutch (Netherlands) sirolimus^dalspiegel:massa/volume:moment:plasma:kwantitatief:
pt-BR Portuguese (Brazil) Sirolimus^basal::Pt:Plas:Qn:
ru-RU Russian (Russian Federation) Сиролимус^остаточная концентрация:МассКонц:ТчкВрм:Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Рапамицин Точка во времени;Момент
tr-TR Turkish (Turkey) Sirolimus^en düşük:KütlKons:Zmlı:Plaz:Kant:
zh-CN Chinese (China) 西罗莫司^波谷:质量浓度:时间点:血浆:定量型:
Synonyms: 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 瑞帕霉素;雷帕霉素 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

Unit Source
mg/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72676-0