72678-6
Venlafaxine+O-desmethylvenlafaxine [Mass/volume] in Serum or Plasma --trough
Active
Term Description
Sample is drawn at the trough (baseline) level of parent drug (venlafaxine).
Part Descriptions
LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Trough levels for therapeutic drug monitoring
LP62421-0 Venlafaxine+O-desmethylvenlafaxine
Venlafaxine (brand name Effexor) is used to treat depression. Venlafaxine extended-release (long-acting) capsules are also used to treat generalized anxiety disorder (GAD; excessive worrying that is difficult to control), social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life), and panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks). Venlafaxine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance.
Source: PubMed Health,
Venlafaxine (Effexor)
LP62421-0 Venlafaxine+O-desmethylvenlafaxine
Norvenlafaxine (brand name Pristiq) is used to treat depression. Also known as O-desmethylvenlafaxine and desvenlafaxine, it is the major active metabolite of venlafaxine, an antidepressant from the serotonin-norepinephrine reuptake inhibitor (SNRI class). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance.
Source: PubMed Health
LOINC Names Get Info
- Fully-Specified Name
- Venlafaxine+O-desmethylvenlafaxine^trough:
MCnc: Pt: Ser/Plas: Qn: - Long Common Name
- Venlafaxine+O-desmethylvenlafaxine [Mass/volume] in Serum or Plasma --trough
- Short Name
- Vnlfxn+ODV Trough SerPl-mCnc
- Display Name
- Venlafaxine+O-desmethylvenlafaxine trough [Mass/Vol]
- Consumer Name Alpha Get Info
- Venlafaxine+O-desmethylvenlafaxine trough, Blood
Part Model Get Info
- Component
- Venlafaxine+O-desmethylvenlafaxine^trough
LP308058-9
- Property
- MCnc
LP6827-2
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser/Plas
LP7576-4
- System Core
- Ser/Plas
LP7576-4
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.69 (NAM)
- Change Reason
- Release 2.69: COMPONENT: Resolve ambiguity in name norvenlafaxine, which has O-desmethyl and N-desmethyl forms, O-desmethyl reported to be the one measured in assays.;
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Venlafaxin+O-desmethylvenlafaxin^Údolní koncentrace: |
| el-GR | Greek (Greece) | Βενλαφαξίνη+Ο-δεσμεθυλοβενλαφαξίνη^ελάχιστα επίπεδα: Synonyms: DRUG/TOX MCnc Pt Qn Βενλαφαξίνη Βενλαφαξίνη+Ο-δεσμεθυλοβενλαφαξίνη ελάχιστα επίπεδα Ο-δεσμεθυλοβενλαφαξίνη Ορός Ορός/Πλάσμα Πλάσμα |
| es-ES | Spanish (Spain) | Venlafaxina+Norvenlafaxina^Valle monitorización terapéutica de fármacos: Synonyms: Cuantitativo Desvelanfaxina |
| es-MX | Spanish (Mexico) | Venlafaxina + O-desmetilvenlafaxina ^ a través: |
| et-EE | Estonian (Estonia) | Venlafaksiin + norenlafaksiin^baas: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Venlafaxine+o-desméthylvenlafaxine^Creux: |
| fr-FR | French (France) | Venlafaxine+O-desméthylvenlafaxine^taux résiduel: |
| fr-BE | French (Belgium) | Venlafaxine+Norvenlafaxine^Creux: Synonyms: Minimum, nadir |
| it-IT | Italian (Italy) | Venlafaxina+O-desvenlafaxina^valore minimo: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM |
| nl-NL | Dutch (Netherlands) | venlafaxine + o-desmethylvenlafaxine^dalspiegel: Synonyms: norvenlafaxine venlafaxine + norvenlafaxine |
| ru-RU | Russian (Russian Federation) | Венлафаксин+Норвенлафаксин^остаточная концентрация: Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Venlafaksin+Norvenlafaksin^en düşük: Synonyms: çukur düzey |
| zh-CN | Chinese (China) | 文拉法辛+O-去甲基文拉法辛^波谷: Synonyms: 一剂药物的初始剂量; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
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LOINC Copyright
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