Version 2.77

Part Description

LP34987-5   Macroprolactin
Monomeric prolactin is the most common form of circulating prolactin. Prolactin also has several isoforms, including the dimeric form ("big-prolactin") that has a molecular weight of ~50 kD and polymeric form ("big-big prolactin") that has a molecular weight of ~ 150 kD). Big-big prolactin, known as macroprolactin, and big prolactin are formed in the circulation after secretion of prolactin from the pituitary. They have a longer half-life than monomeric prolactin are not biologically active. However, typical prolactin assays do not differentiate between the different forms of prolactin, and the presence of big and big-big prolactin can lead to a false diagnosis of hyperprolactinemia. Methods such as PEG precipitation can separate macroprolactin and big prolactin from monomeric prolactin in order to obtain a more accurate measurement of biologically active prolactin, and chromatography can be used to further characterize the isoforms if necessary. PMCID: PMC3719302 Source: Regenstrief LOINC,

Fully-Specified Name


Additional Names

Short Name
Macroprolactin SerPl Ql
Display Name
Macroprolactin Ql
Consumer Name Alpha Get Info
Macroprolactin, Blood

Example Answer List: LL2010-8

Source: Estonian Society of Laboratory Medicine
Answer Code Score Answer ID
PositiveCopyright ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright ID:260385009 Negative (qualifier value) LA6577-6
Borderline LA4259-3

Basic Attributes

First Released
Version 2.42
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Macroprolactina:PrThr:Punto temporal:Suero o Plasma:Ord:
es-MX Spanish (Mexico) Macroprolactina:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:
et-EE Estonian (Estonia) Makroprolaktiin:PrThr:Pt:S/P:Ord:
Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CA French (Canada) Macroprolactine:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:
fr-FR French (France) Macroprolactine:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:
fr-BE French (Belgium) Macroprolactine:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:
it-IT Italian (Italy) Macroprolattina:PrThr:Pt:Siero/Plasma:Ord:
Synonyms: Chimica Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) macroprolactine:aanwezigheid:moment:serum of plasma:ordinaal:
pt-BR Portuguese (Brazil) Macroprolactina:Limiar:Pt:Soro/Plas:Ord:
ru-RU Russian (Russian Federation) Макропролактин:PrThr:ТчкВрм:Сыв/Плаз:Пор:
Synonyms: Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Makroprolaktin:MevcEşik:Zmlı:Ser/Plaz:Srl:
Synonyms: Mevcut
zh-CN Chinese (China) 巨催乳素:存在情况或阈值:时间点:血清/血浆:序数型:
Synonyms: bbPRL;IgG 结合型促乳激素;巨促乳激素;巨促乳泌素;巨促乳素;巨催乳激素;巨泌乳激素;巨泌乳素;巨催乳素(bbPRL、IgG 结合型促乳激素、巨促乳激素、巨促乳泌素、巨促乳素、巨催乳激素、巨泌乳激素、巨泌乳素) 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 血清或血浆

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