72743-8
Normeperidine [Mass/volume] in Saliva (oral fluid) by Confirmatory method
Active
Part Descriptions
LP14726-1 Normeperidine
Normeperidine is a major metabolite of meperidine and very weak analgesic. It is half as potent as meperidine as an analgesic but 2-3 times more potent as a convulsant. The half-life of normeperidine is increased in patient's with renal failure. Symptoms of normeperidine accumulation progress from irritability to tremors and generalized seizures. Such patients are known to have high plasma concentrations of normeperidine. When naloxone is administered for normeperidine-induced seizures, an exacerbation of the seizures occurs due to antagonism of the seizure-suppressing effects of meperidine.
Source: Regenstrief LOINC,
PMID:10620557
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Normeperidine:
MCnc: Pt: Saliva: Qn: Confirm - Long Common Name
- Normeperidine [Mass/volume] in Saliva (oral fluid) by Confirmatory method
- Short Name
- Normeperidine Sal Cfm-mCnc
- Display Name
- Normeperidine Confirm (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- Normeperidine, Saliva
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 10466
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Normeperidin: |
| el-GR | Greek (Greece) | Νορμεπεριδίνη: Synonyms: DRUG/TOX MCnc Pt Qn Επιβεβαίωση Νορμεπεριδίνη Σίελος |
| es-ES | Spanish (Spain) | Normeperidina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Normeperidina: |
| et-EE | Estonian (Estonia) | Normeperidiin: Synonyms: Juhuslik Kvantitatiivne Sülg |
| fr-CA | French (Canada) | Normépéridine: |
| fr-FR | French (France) | Norpéthidine: |
| fr-BE | French (Belgium) | Normépéridine: |
| it-IT | Italian (Italy) | Normeperidina: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | normeperidine: |
| ru-RU | Russian (Russian Federation) | Нормеперидин: Synonyms: Количественный Массовая концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | Normeperidin: Synonyms: Teyid |
| zh-CN | Chinese (China) | 去甲基哌替啶: Synonyms: 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| ng/mL | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://