Version 2.77

Part Descriptions

LP34568-3   Norbuprenorphine
Buprenorphine (tradename Buprenex), is a long-lasting, high affinity opioid that acts on the same receptors as heroin and morphine but does not produce the same intense high or dangerous side effects. It is used for the treatment of pain and opioid dependence. The major buprenorphine metabolites are norbuprenorphine, buprenorphine-3-glucuronide (B3G), and norbuprenorphine-3-glucuronide (N3G). The analysis of buprenorphine and metabolites is performed to monitor compliance to drug therapy. Source: Regenstrief LOINC

LP34568-3   Norbuprenorphine
Norbuprenorphine is the primary active metabolite of buprenorphine, and its mean steady-state plasma concentration is comparable to or even exceeds that of buprenorphine following sublingual buprenorphine absorption (Kuhlman et al., 1998). It is likely to contribute to the overall pharmacological effects of buprenorphine. Buprenorphine and norbuprenorphine displayed distinct pharmacological properties at mu-opioid, delta-opioid, and kappa-opioid receptors and the ORL1 receptor. PMID: 11303059 Source: Regenstrief LOINC

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

Fully-Specified Name

Component
Norbuprenorphine
Property
MCnc
Time
Pt
System
Saliva
Scale
Qn
Method
Confirm

Additional Names

Short Name
Norbuprenorphine Sal Cfm-mCnc
Display Name
Norbuprenorphine Confirm (Sal) [Mass/Vol]
Consumer Name Alpha Get Info
Norbuprenorphine, Saliva

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
5523

Member of these Groups Get Info

LOINC Group Group Name
LG50147-4 Norbuprenorphine|ANYProp|ANYTm|ANYSys|ANYMeth

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Norbuprenorfina:Concentración de masa:Punto temporal:Saliva:Qn:Confirmatorio
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Norbuprenorfina:Concentración de masa:Punto temporal:Saliva:Cuantitativo:Confirmar
et-EE Estonian (Estonia) Norbuprenorfiin:MCnc:Pt:Sal:Qn:Kinnitav
Synonyms: Juhuslik Kvantitatiivne Sülg
fr-CA French (Canada) Norbuprénorphine:Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:Confirmation
fr-FR French (France) Norbuprénorphine:Masse/Volume:Ponctuel:Salive:Numérique:Confirmation
fr-BE French (Belgium) Norbuprenorphine:Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:Confirmé
it-IT Italian (Italy) Norbuprenorfina:MCnc:Pt:Saliva:Qn:Conferma
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) norbuprenorfine:massa/volume:moment:speeksel:kwantitatief:bevestiging
pt-BR Portuguese (Brazil) Norbuprenorfina::Pt:Saliva:Qn:Confirmatório
ru-RU Russian (Russian Federation) Норбупренорфин:МассКонц:ТчкВрм:Слюна:Колич:Подтверждать
Synonyms: Количественный Массовая концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Norbuprenorfin:KütlKons:Zmlı:Tükürük:Kant:Onay
Synonyms: Teyid
zh-CN Chinese (China) 去甲基丁丙诺啡:质量浓度:时间点:唾液:定量型:毒理学确认试验
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 津;津液;涎 确认方法;确认法;确认试验 脱甲基丁丙诺啡;丁丙诺啡代谢产物;去甲丁丙诺啡;去甲基布诺啡;去甲布诺啡 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72746-1