Version 2.77

Descriptions

Buprenorphine (tradename Buprenex), is a long-lasting, high affinity opioid that acts on the same receptors as heroin and morphine but does not produce the same intense high or dangerous side effects. It is used for the treatment of pain and opioid dependence. The major buprenorphine metabolites are norbuprenorphine, buprenorphine-3-glucuronide (B3G), and norbuprenorphine-3-glucuronide (N3G). The analysis of buprenorphine and metabolites is performed to monitor compliance to drug therapy. Source: Regenstrief LOINC

Norbuprenorphine is the primary active metabolite of buprenorphine, and its mean steady-state plasma concentration is comparable to or even exceeds that of buprenorphine following sublingual buprenorphine absorption (Kuhlman et al., 1998). It is likely to contribute to the overall pharmacological effects of buprenorphine. Buprenorphine and norbuprenorphine displayed distinct pharmacological properties at mu-opioid, delta-opioid, and kappa-opioid receptors and the ORL1 receptor. PMID: 11303059 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Norbuprenorphine
Part Type
Component (Describes the core component or analyte measured)
Created On
2004-09-03
Construct for LOINC Short Name
Norbuprenorphine

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 去甲基丁丙诺啡
Synonyms: 脱甲基丁丙诺啡;丁丙诺啡代谢产物;去甲丁丙诺啡;去甲基布诺啡;去甲布诺啡
fr-CA French (Canada) Norbuprénorphine
et-EE Estonian (Estonia) Norbuprenorfiin
es-ES Spanish (Spain) Norbuprenorfina
it-IT Italian (Italy) Norbuprenorfina
tr-TR Turkish (Turkey) Norbuprenorfin
ru-RU Russian (Russian Federation) Норбупренорфин
nl-NL Dutch (Netherlands) norbuprenorfine
fr-BE French (Belgium) Norbuprenorphine