72759-4
Codeine [Mass/volume] in Saliva (oral fluid) by Confirmatory method
Active
Part Descriptions
LP16093-4 Codeine
Codeine is a plant alkaloid of opium that relieves acute or chronic pain and suppresses cough. [https://pubchem.ncbi.nlm.nih.gov/compound/codeine#section=Top] Codeine is extensively prescribed throughout the world and is frequently combined with non-opiate drugs including acetaminophen and aspirin. Codeine is a tenth as potent as morphine and is considered its prodrug. A small portion of codeine is metabolized by the enzyme CYP2D6 to morphine which is responsible for the analgesic affect of codeine. Variability of the activity of CYP2D6 based on the patient's genotype can influence the ability of codeine to relieve pain.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition; Carl A. Burtis; David E. Bruns, p580)
Source: Regenstrief LOINC
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Codeine
- Property
- MCnc
- Time
- Pt
- System
- Saliva
- Scale
- Qn
- Method
- Confirm
Additional Names
- Short Name
- Codeine Sal Cfm-mCnc
- Display Name
- Codeine Confirm (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- Codeine, Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 6570
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37586-1 | Codeine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Codeina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Codeína: |
| et-EE | Estonian (Estonia) | Kodeiin: Synonyms: Juhuslik Kvantitatiivne Sülg |
| fr-CA | French (Canada) | Codéine: |
| fr-FR | French (France) | Codéine: |
| fr-BE | French (Belgium) | Codéïne: |
| it-IT | Italian (Italy) | Codeina: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | codeïne: |
| pt-BR | Portuguese (Brazil) | Codeína: |
| ru-RU | Russian (Russian Federation) | Кодеин: Synonyms: Количественный Массовая концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | Kodein: Synonyms: Teyid |
| zh-CN | Chinese (China) | 可待因: Synonyms: C18H21NO3; |
Example Units
| Unit | Source |
|---|---|
| ng/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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