72879-0
Deprecated CYP2C19 gene drug metabolism analysis overall interpretation [Interpretation] in Blood, Tissue or Saliva Qualitative by Molecular genetics method
Deprecated
Status Information
- Status
- DEPRECATED
- Reason
- Duplicate
| Map-To | Long Common Name | Mapping Guidance |
|---|---|---|
| 79714-2 | CYP2C19 gene product metabolic activity interpretation in Blood or Tissue Qualitative by Molecular genetics method |
Term Description
Overall predicted phenotype for drug metabolism for all markers and/or individual CYP2C19 alleles identified in a patient. The predicted phenotypes are derived from reference literature.
Source: Regenstrief LOINC
Part Description
LP97107-4 CYP2C19 gene
The CYP2C19 gene (cytochrome P450, family 2, subfamily C, polypeptide 19) [HGNC Gene ID:2621] is located on chromosome 10q24. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008] [NCBI Gene ID:1557]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- CYP2C19 gene drug metabolism analysis overall interpretation
- Property
- Imp
- Time
- Pt
- System
- Bld/Tiss/Sal
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- Deprecated CYP2C19 drg metab interp Bld/T/S-Imp
- Display Name
- CYP2C19 gene drug metabolism analysis overall interpretation Molgen Ql (Bld/Tiss/Sal) [Interp]
- Consumer Name Alpha Get Info
- CYP2C19 gene drug metabolism interpretation
Example Answer List: LL605-7
Source: Regenstrief LOINC| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Ultrarapid metabolizer | LA10315-2 | ||
| Extensive metabolizer | LA10316-0 | ||
| Intermediate metabolizer | LA10317-8 | ||
| Poor metabolizer | LA9657-3 | ||
| InconclusiveCopyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value) | LA9663-1 | ||
| Failure | LA9664-9 |
Basic Attributes
- Class
- MOLPATH.MUT
- Type
- Laboratory
- First Released
- Version 2.44
- Last Updated
- Version 2.67
- Change Reason
- Corrected Scale from "Nom" to "Ord" since results are ordinal.
- Order vs. Observation
- Observation
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Gen CYP2C19 Interpretación total del metabolismo de drogas: |
| es-MX | Spanish (Mexico) | Interpretación general del análisis del metabolismo de fármacos del gen CYP2C19: |
| fr-FR | French (France) | CYP2C19 gène métabolisme des médicaments interprétation globale: |
| it-IT | Italian (Italy) | CYP2C19, gene , farmaci, interpretazione complessiva analisi metabolismo: Synonyms: Gene CYP2C19 Genetica molecolare Impressione/interpretazione di studio Interpretazione complessiva di analisi del metabol Mutazione genica Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Sangue, Tessuto o Saliva Tessuto & |
| pt-BR | Portuguese (Brazil) | CYP2C19 gene análise do metabolismo de drogas interpretação global: |
| ru-RU | Russian (Russian Federation) | CYP2C19 ген наркотик метаболизм анализ общая интерпретация: Synonyms: Впечатление/интерпретация исследования Кровь Кровь или Ткань Кровь, Ткань или Слюна лекарства метаболизма анализ общая интерпретация Наркотик Порядковый Ткань и мазки Точка во времени; |
| tr-TR | Turkish (Turkey) | CYP2C19 geni ilaç metabolizması analizi tüm değerlendirilme: Synonyms: KISALTILMIŞINA BAK |
| zh-CN | Chinese (China) | CYP2C19 基因 药物代谢分析总体解释: Synonyms: Cytochrome P450, family 2, subfamily C, polypeptide 19; |
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