Version 2.77

Part Descriptions

LP15182-6   Tacrolimus
Tacrolimus (also known as FK-506 or Prograf) is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis. It has strong immunosuppressive properties and is commonly used to prevent allograft rejection in transplant recipients. One of its modes of action is to prevent T-lymphocyte activation. Source: National Library of Medicine, MeSH 2006

LP15182-6   Tacrolimus
Tacrolimus (also called FK-506 or fujimycin, Prograf, Advagraf, or Protopic) is amacrolide lactone, calcineurin inhibitor immunosuppresent used mainly after allogeneic organ transplant to lower the risk of organ rejection. It possesses strong immunosuppressive activity by preventing the activation by of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, TH2-mediated diseases such as Kimura's disease, and the skin condition vitiligo. There are potentially severe side effects from doses that are either too low or too high; inadequate tacrolimus concentrations may result in rejection of the transplanted organ, while high levels may lead to severe adverse effects includin nephrotoxicity, neurotoxicity, gastrointestinal disturbances, diabetogenesis, hypertension and malignant complications. [Wikipedia: Tacrolimus] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Tacrolimus

Fully-Specified Name

Component
Tacrolimus induced neutrophil Ab.IgG
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
Flow cytometry

Additional Names

Short Name
Tacrolimus (neut) IgG SerPl Ql FC
Display Name
Tacrolimus induced neutrophil IgG FC Ql
Consumer Name Alpha Get Info
Tacrolimus induced neutrophil IgG, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
72909-5 Drug induced neutrophil Ab panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Tacrolimus Acs. IgG neutrófilos inducidos:PrThr:Punto temporal:Suero o Plasma:Ord:Citometria de flujo (FC)
es-MX Spanish (Mexico) Ab.IgG de neutrófilos inducidos por tacrolimus:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Citometría de flujo (FC)
fr-FR French (France) Polynucléaires neutrophiles anticorps IgG induits par tacrolimus:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Cytométrie de flux
it-IT Italian (Italy) Tacrolimus Ab.IgG neutrofili indotti da:PrThr:Pt:Siero/Plasma:Ord:Citometria a flusso
Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) FK-506 Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) tacrolimus geïnduceerd neutrofiel As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:flowcytometrie
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Tacrolimus neutrófilos induzida Ac.IgG::Pt:Soro/Plas:Ord:Citometria de fluxo
ru-RU Russian (Russian Federation) Такролимус индуцированный нейтрофил Ат.IgG:PrThr:ТчкВрм:Сыв/Плаз:Пор:Проточная цитометрия
Synonyms: Антитело индуцированные к нейтрофилам Ат Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Takrolimus uyarılmış nötrofil Ab.IgG:MevcEşik:Zmlı:Ser/Plaz:Srl:Akış sitometri
Synonyms: Ak Ak.IgG Akış hücremetresi Mevcut
zh-CN Chinese (China) 他克莫司 诱导型嗜中性粒细胞抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:流式细胞测量术
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 PMN;中性;中性白细胞;中性粒细胞;嗜中性;嗜中性白细胞;多形核;多形核白细胞;多形核粒细胞;多形核粒细胞（PMN） 中性白细胞 Ab 中性白细胞 Ab.IgG 中性白细胞 IgG 中性白细胞抗体 中性白细胞抗体.IgG 中性粒细胞 Ab 中性粒细胞 Ab.IgG 中性粒细胞 IgG 中性粒细胞抗体 中性粒细胞抗体.IgG 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 动态 嗜中性白细胞 Ab 嗜中性白细胞 Ab.IgG 嗜中性白细胞 IgG 嗜中性白细胞抗体 嗜中性白细胞抗体.IgG 嗜中性粒细胞 Ab 嗜中性粒细胞 Ab.IgG 嗜中性粒细胞 IgG 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 普乐可复 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 粒细胞 Ab 粒细胞抗体 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆 诱导型（诱导性、诱发型）嗜中性粒细胞（中性粒细胞）抗体 诱导型（诱导性、诱发型）嗜中性粒细胞（中性粒细胞）抗体.IgG

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72946-7