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Term Description

The % activated natural killer (NK) cells can be determined by comparing the number of activated NK cells (CD3-CD16+CD56+HLA-DR+) out of 100 NK cells (CD3-CD16+CD56+). The submitter's lab uses HLA DR antibodies (HLA DR+) for late activation of NK cells within a subpopulation of NK cells that lack CD3 expression (CD3-) and express CD16 and CD56 (CD16+, CD56+).

Part Description

LP172587-0   Cells.CD3-CD16+CD56+HLA-DR+
Activated natural killer cells are large granular lymphocytes that arise from the bone marrow and play a major role in preventing growth of tumor and virally-infected cells. They usually lack CD3 expression, but express CD2, CD16, CD56, CD57, and sometimes CD8. They are to be distinguished from natural killer T cells (NKT cells) which do carry the CD3 marker. Natural killer cell populations may be increased or decreased with various immunologic abnormalities. Activated NK cells release cytotoxic (cell-killing) granules which destroy altered cells. Source: Regenstrief LOINC, Natural Killer (NK) cells

LOINC Names Get Info

Fully-Specified Name
Cells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+:NFr:Pt:Bld:Qn:Flow cytometry
Long Common Name
CD3-CD16+CD56+HLA-DR+ (activated Natural Killer) cells/Cells.CD3-CD16+CD56+ in Blood by Flow cytometry (FC)
Short Name
NK activated/NK NFr Bld FC
Display Name
CD3-CD16+CD56+HLA-DR+ (activated Natural Killer) cells/Cells.CD3-CD16+CD56+ FC (Bld)
Consumer Name Alpha Get Info
CD3-CD16+CD56+HLA-DR+ (activated natural killer) cells/Cells.CD3-CD16+CD56+, Blood

Part Model Get Info

  • Component
    Cells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+
    LP445190-4
    • Analyte
      Cells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+
      LP445190-4
      • Component Numerator
        Cells.CD3-CD16+CD56+HLA-DR+
        LP172587-0
        • Component Numerator Core
          Cells.CD3-CD16+CD56+HLA-DR+
          LP172587-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        Cells.CD3-CD16+CD56+
        LP444764-7
        • Component Denominator Core
          Cells.CD3-CD16+CD56+
          LP444764-7
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    NFr
    LP6838-9
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Flow cytometry
    LP6274-7

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Buňky.CD3-CD16+CD56+HLA-DR+/100 buněk.CD3-CD16+CD56+:Početní podíl:Časový bod:Krev:Kvantitativní:Průtoková cytometrie
es-MXSpanish (Mexico)Células CD3-CD16 + CD56 + HLA-DR + / 100 células CD3-CD16 + CD56 +:Fracción numérica:Punto temporal:Sangre:Cuantitativo:Citometría de flujo (FC)
es-ESSpanish (Spain)Células CD3-CD16+CD56+HLADR+/Células CD3-CD16+CD56+:Fracción numérica:Punto temporal:Sangre:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
fr-FRFrench (France)CD3-CD16+CD56+HLA-DR+/CD3-CD16+CD56+:Fraction de nombres:Ponctuel:Sang:Numérique:Cytométrie de flux
it-ITItalian (Italy)Cellule.CD3-CD16+CD56+HLA-DR+/Cellule.CD3-CD16+CD56+:NFr:Pt:Sangue:Qn:Citometria a flusso
Synonyms: Cellule CD3 Cellule CD3+CD16+ Cellule CD3+CD16+CD56+ Cellule CD3-CD16+ Cellule CD3-CD16+CD56+ Cellule CD3-CD16+CD56+HLA-DR+ Citometria a flusso (FC) Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
nl-NLDutch (Netherlands)cellen.CD3-CD16+CD56+HLA-DR+/100 cellen.CD3-CD16+CD56+:getalsfractie:moment:bloed:kwantitatief:flowcytometrie
Synonyms: natural killer cells; ''natural killer''-cellen; NK-cellen
pl-PLPolish (Poland)Komórki.CD3-CD16+CD56+HLA-DR+/komórki.CD3-CD16+CD56+:frakcja liczbowa:punkt w czasie:krew:ilościowy:cytometria przepływowa (FC)
Synonyms: CD16 Komórki CD3+CD16+ Komórki CD3+CD16+CD56+ Komórki CD3-CD16+CD56+ Komórki CD3-CD16+CD56+HLA-DR+
zh-CNChinese (China)细胞.CD3-CD16+CD56+HLA-DR+/细胞.CD3-CD16+CD56+:计数型分数:时间点:全血:定量型:流式细胞测量术
Synonyms: CD3+CD16+CD56+细胞 CD3+CD16+细胞 CD3-CD16+CD56+HLA-DR+细胞 CD3-CD16+CD56+细胞 CD3-CD16+细胞 CD3细胞 HLA 抗原;人类白细胞抗原;human leukocyte antigen I3 Leu11;Leu-11;Leu11b;Leu-11B Leu19;Leu-19;NCAM;NKH1;神经细胞粘附分子;神经细胞粘附分子（Neural cell adhesion molecule，NCAM）;神经细胞黏附分子 Leu4;Leu-4;T3 人白细胞抗原 人类白细胞抗原 人类白细胞抗原（Human Leukocyte Antigen，HLA） 动态 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 白细胞抗原 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 血;血液

Example Units

UnitSource
%Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=73810-4