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Term Description

The percent inhibition by heparin is determined by adding excess heparin (high-dose heparin) to the patient's serum. Testing is performed to increase the specificity of the assay and confirm a positive heparin induced antibody result. Inhibition of a positive result by 50% or more reduction in the optical density is considered confirmatory and characteristic of Type II heparin induced thrombocytopenia (HIT) antibodies.

Part Description

LP172606-8   Percent heparin inhibition
Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. In HIT, the immune system forms antibodies against heparin when it is bound to a protein called platelet factor 4 (PF4). These antibodies are usually of the IgG class, which form a complex with heparin and PF4 in the bloodstream. The tail of the antibody then binds to the FcγIIa receptor, a protein on the surface of the platelet. This results in platelet activation and the formation of platelet microparticles, which initiate the formation of blood clots; the platelet count falls as a result, leading to thrombocytopenia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia

LOINC Names Get Info

Fully-Specified Name
Percent heparin inhibition:Ratio:Pt:Ser:Qn:
Long Common Name
Percent heparin inhibition [Ratio] in Serum
Short Name
Prcnt hep inhibited Ser-Rto
Display Name
Percent heparin inhibition (S) [Ratio]
Consumer Name Alpha Get Info
Percent heparin inhibition, Blood

Part Model Get Info

  • Component
    Percent heparin inhibition
    LP172606-8
    • Analyte
      Percent heparin inhibition
      LP172606-8
      • Component Numerator
        Percent heparin inhibition
        LP172606-8
        • Component Numerator Core
          Percent heparin inhibition
          LP172606-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Ratio
    LP6852-0
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.44 (MIN)
Order vs. Observation
Observation

Formula (Readable)

% heparin inhibition = 1-([Heparin induced platelet Ab.IgG with excess heparin - negative control]/[Heparin induced platelet Ab.IgG without excess heparin - negative control]) x 100

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Heparin procentuální inhibice:Poměr:Časový bod:Sérum:Kvantitativní:
el-GRGreek (Greece)Ποσοστό αναστολής ηπαρίνης:Ratio:Pt:Ορός:Qn:
Synonyms: Pt Qn Ratio SERO Ηπαρίνη Ορός Ποσοστό αναστολής ηπαρίνης
es-ESSpanish (Spain)Porcentaje inhibitorio de heparina:Fracción:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Inhibición porcentual de la heparina:Proporción:Punto temporal:Suero:Cuantitativo:
fr-CAFrench (Canada)Héparine pourcentage inhibition:Ratios:Temps ponctuel:Sérum:Quantitatif:
fr-FRFrench (France)Héparine pourcentage inhibition:Ratio:Ponctuel:Sérum:Numérique:
it-ITItalian (Italy)Percentuale inibizione di eparina:Rapporto:Pt:Siero:Qn:
Synonyms: Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)percentage heparine-remming:verhouding:moment:serum:kwantitatief:
ru-RURussian (Russian Federation)Процент гепарин ингибирование:Отношение:ТчкВрм:Сыв:Колич:
Synonyms: Количественный Коэффициент;Соотношение;Пропорция Сыворотка Точка во времени;Момент
tr-TRTurkish (Turkey)Heparin inhibisyon yüzdesi:Oran:Zmlı:Ser:Kant:
zh-CNChinese (China)肝素抑制百分数:比率:时间点:血清:定量型:
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 来自于不同体系的两个观察指标之比;比;比值 肝制凝素;肝磷脂 肝素抑制百分比;肝素抑制百分率;肝素抑制率 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

UnitSource
%Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=73817-9