Version 2.80

Part Description

LP15884-7   Tetrahydrodeoxycortisol
Tetrahydrodeoxycortisol (THS) is a mineralocorticoid the main urinary metabolite of 11-deoxycortisol. THS excretion is significantly associated with tetrahydroaldosterone excretion, total androgen excretion, and cortisol metabolites. Aldosterone synthesis is highly heritable and is affected by genotype at CYP11B1. Variation in the region of chromosome 8 including the genes steroid 11-beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism; differences in 11-hydroxylation efficiency can have downstream effects on mineralocorticoid synthesis. Such effects may be of relevance to the development of low-renin essential hypertension. Genotype differences in CYP11B1 explains approximately 5% of the variance in urinary THS excretion in the population. Excretion of THS is heritable (19.4%) and the T-allele of the -344 C/T polymorphism of CYP11B2 is more strongly associated with higher THS levels than the C-allele. PMID: 16984984, PMID: 15522937, PMID: 15272911. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database , Tetrahydrodeoxycortisol

Fully-Specified Name

Component
Tetrahydrodeoxycortisol
Property
SRat
Time
24H
System
Urine
Scale
Qn
Method

Additional Names

Long Common Name
Tetrahydrodeoxycortisol [Moles/time] in 24 hour Urine
Short Name
TH-DC 24h Ur-sRate
Display Name
Tetrahydrodeoxycortisol (24H U) [Moles/Time]
Consumer Name Alpha Get Info
Tetrahydrodeoxycortisol, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.44 (MIN)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Τετραϋδροδεοξυκορτιζόλη:SRat:24H:Ούρα:Qn:
Synonyms: SRat Τετραϋδροδεοξυκορτιζόλη
es-ES Spanish (Spain) Tetrahidrodesoxicortisol:Indice de susbtancia:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Tetrahidrodesoxicortisol:Tasa de sustancia:24H:Orina:Cuantitativo:
et-EE Estonian (Estonia) Tetrahüdrodeoksükortisool:SRat:24 tunni:U:Qn:
Synonyms: Aine määr Kvantitatiivne Uriin
fr-FR French (France) Tétrahydro-11-déoxycortisol:Moles/Temps:24H:Urine:Numérique:
it-IT Italian (Italy) Tetraidrodeossicortisolo:SRat:24h:Urine:Qn:
Synonyms: 24 Ore Chimica Tasso di sostanza
nl-NL Dutch (Netherlands) tetrahydrodeoxycortisol:mol/tijd:24 uur:urine:kwantitatief:
Synonyms: 24U
pt-BR Portuguese (Brazil) Tetrahidrodeoxicortisol::24H:Urina:Qn:
ru-RU Russian (Russian Federation) Тетрагидродеоксикортизол:МольРасх:24 часа:Моча:Колич:
Synonyms: Количественный Молярная скорость;Молярный расход Тетрагидродезоксикортизол
tr-TR Turkish (Turkey) Tetrahidrodeoksikortizol:SubHz:24Sa:İdrar:Kant:
zh-CN Chinese (China) 四氢脱氧皮质醇:物质的量速率:24小时:尿液:定量型:
Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 TH-DC;四氢-11-脱氧皮质醇;四氢脱氧皮质甾醇;四氢脱氧皮醇 克分子速率;克分子速率(单位时间);摩尔速率;摩尔速率(单位时间);物质的量速率(单位时间) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉

Example Units

Unit Source
umol/(24.h) Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=73843-5