73863-3
Allo-tetrahydrocortisol [Moles/volume] in Urine
Active
Part Description
LP17229-3 Allo-tetrahydrocortisol
Allo-tetrahydrocortisol (5a-Tetrahydrocortisol) is a normal human metabolite. However its increased ratio (5alpha-Tetrahydrocortisol + Tetrahydrocortisol) over Tetrahydrocortisone in urine is the biochemical marker for the syndrome of apparent mineralocorticoid excess (AME). AME is a heritable form of hypertension due to an inborn error of cortisol metabolism and is characterized by hypokalemia and low renin levels despite subnormal or normal levels of aldosterone and other known mineralocorticoids. The syndrome is attributable to congenital deficiency of the enzyme 11 beta-hydroxydehydrogenase (11 beta-HSD), which converts cortisol to biologically inactive cortisone. This results in a prolonged half-life of Cortisol, which acts at the kidney level as a potent mineralocorticoid. [PMID :8732999].
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Allo-tetrahydrocortisol
Fully-Specified Name
- Component
- Allo-tetrahydrocortisol
- Property
- SCnc
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Allo-THF Ur-sCnc
- Display Name
- Allo-tetrahydrocortisol (U) [Moles/Vol]
- Consumer Name Alpha Get Info
- Allo-tetrahydrocortisol, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.44
- Last Updated
- Version 2.44
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG37139-9 | Allo-tetrahydrocortisol| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Alo-tetrahidrocortisol: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Alo-tetrahidrocortisol: |
et-EE | Estonian (Estonia) | Allo-tetrahüdrokortisool: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Uriin |
fr-CA | French (Canada) | Allo-tétrahydrocortisol: |
fr-FR | French (France) | Allo-tétrahydrocortisol: |
fr-BE | French (Belgium) | Allo-tétrahydrocortisol: |
it-IT | Italian (Italy) | Allo-tetraidrocortisolo: Synonyms: Chimica Concentrazione di Sostanza Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | allo-tetrahydrocortisol: |
pt-BR | Portuguese (Brazil) | Allo-tetrahidrocortisol: |
ru-RU | Russian (Russian Federation) | Алло-тетрагидрокортизол: Synonyms: Количественный Молярность; |
tr-TR | Turkish (Turkey) | Allo-tetrahidrokortizol: |
zh-CN | Chinese (China) | 别-四氢皮质醇: Synonyms: Allo-THF; |
Example Units
Unit | Source |
---|---|
umol/L | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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