73913-6

Glycine in CSF/Glycine in plasma

Active

Term Description

Relative substance concentration of glycine in CSF-to-plasma is measured for the diagnosis of glycine encephalopathy.

Part Description

LP172773-6 Glycine CSF/Glycine plas
Individuals with elevated CSF glycine concentration along with an increased CSF-to-plasma glycine ratio are suspected of having glycine encephalopathy,also known as nonketotic hyperglycinemia (NKH). NKH is an autosomal recessive condition of glycine metabolism in which large quantities of glycine accumulate in all body tissues, including the brain. Several ofrms of the disease existing, varying severity of symptoms and time of onset. Most cases present in the neonatal period and are usually severe, manifesting in the first hours to days of life with progressive lethargy, hypotonia, and myoclonic jerks leading to apnea and often death. When presenting in infancy, 50% of cases are mild and the other half are severe. Patients present with hypotonia, developmental delay, and seizures. The remainder of cases (very few) are atypical and range from milder disease, with onset from late infancy to adulthood, to rapidly progressing and severe disease with late onset. Source: Regenstrief LOINC, PMID: 20301531

LOINC Names Get Info

Fully-Specified Name: Glycine CSF/Glycine plas:RelSCnc:Pt:Plas+CSF:Qn:
Long Common Name: Glycine in CSF/Glycine in plasma
Short Name: Glycine CSF/Glycine plas
Display Name: Glycine in CSF/Glycine in plasma (P+CSF) [Relative moles/Vol]
Consumer Name Alpha Get Info: Glycine in CSF/Glycine in Plasma, Blood+Spinal fluid

Part Model Get Info

Component
Glycine CSF/Glycine plas
LP172773-6
- Analyte
  Glycine CSF/Glycine plas
  LP172773-6
  - Component Numerator
    Glycine CSF
    LP172771-0
    - Component Numerator Core
      Glycine CSF
      LP172771-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Glycine plas
    LP172806-4
    - Component Denominator Core
      Glycine plas
      LP172806-4
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
RelSCnc
LP21275-0
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Plas+CSF
LP30184-3
- System Core
  Plas+CSF
  LP30184-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.44
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 12673

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Glycin mozkomíšní mok/glycin plazma:Relativní látková koncentrace:Časový bod:Plazma a mozkomíšní mok:Kvantitativní:
el-GR	Greek (Greece)	Γλυκίνη ΕΝΥ/Γλυκίνη πλάσματος:RelSCnc:Pt:Πλάσμα+ΕΝΥ:Qn: Synonyms: CHEM Pt Qn RelSCnc Γλυκίνη Γλυκίνη ΕΝΥ Γλυκίνη πλάσματος ΕΝΥ Πλάσμα Πλάσμα+ΕΝΥ
es-ES	Spanish (Spain)	Glicina liquido cefalorraquideo/Glicina plasma:Concentración relativa de sustancias:Punto temporal:Plasma y LCR:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Glicina CSF / Glicina plas:Concentración relativa de sustancias:Punto temporal:Plasma y LCR:Cuantitativo:
fr-FR	French (France)	Glycine LCR/glycine plasma:Concentration molaire relative:Ponctuel:Plasma+Liquide céphalorachidien:Numérique:
it-IT	Italian (Italy)	Glicina LCS/Glicina plas:RelSCnc:Pt:Plasma+LCS:Qn: Synonyms: Chimica Concentrazione di Sostanza Relativa Glicina in LCS Liquido cerebrospinale Plasma Plasma & LCS Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	glycine CSF/glycine plasma:relatieve mol/volume:moment:plasma en liquor cerebrospinalis:kwantitatief:
ru-RU	Russian (Russian Federation)	Глицин ЦСЖ/Глицин плаз:ОтнМолКонц:ТчкВрм:Плазма+ЦСЖ:Колич: Synonyms: Глицин в плазме Глицины в плазме Количественный Относительная молярная концентрация Плазма Точка во времени;Момент Цереброспинальная жидкость
tr-TR	Turkish (Turkey)	Glisin BOS/Glycine plas:GörSubKons:Zmlı:Plaz+BOS:Kant:
zh-CN	Chinese (China)	脑脊液甘氨酸/血浆甘氨酸:相对物质的量浓度:时间点:血浆+脑脊液:定量型: Synonyms: CSF CSF 甘氨酸;甘氨酸 CSF;脑脊髓液甘氨酸 CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Gly;氨基醋酸;革氨酸化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间甘氨酸 plas;甘氨酸血浆甘氨酸血浆相对克分子浓度;相对摩尔浓度脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液血浆 & 脑脊液;血浆 & 脑脊髓液;血浆+脑脊髓液;血浆与脑脊液;血浆与脑脊髓液

Example Units

Unit	Source
{ratio}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.