73970-6

Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free DNA by Dosage of chromosome-specific cfDNA

Active

Term Description

The probability risk for trisomy 21 can be determined based on dosage of chromosome specific circulating cell free (ccf) DNA in maternal plasma, the mother's current age and gestational age. The ccf DNA includes both fetal and maternal DNA. This code is based, but not limited in use to, the submitter's test, Harmony Prenatal Test, which is a non-invasive prenatal test intended to aid in the risk determination of fetal sex chromosome aneuploidy as well as trisomy 13, 18 and 21 in women with singleton pregnancies of at least 10 weeks gestational age.

LOINC Names Get Info

Fully-Specified Name: Fetal trisomy 21 risk:Likelihood:Pt:Plas.cfDNA:Qn:Dosage of chromosome specific cf DNA
Long Common Name: Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free DNA by Dosage of chromosome-specific cfDNA
Short Name: Fet Ts 21 risk Plas.cfDNA Qn
Display Name: Trisomy 21 risk Dosage of chromosome-specific cfDNA Qn (cfDNA)
Consumer Name Alpha Get Info: Fetal Trisomy 21 risk

Part Model Get Info

Component
Fetal trisomy 21 risk
LP410748-0
- Analyte
  Fetal trisomy 21 risk
  LP410748-0
  - Component Numerator
    Fetal trisomy 21 risk
    LP410748-0
    - Component Numerator Core
      Fetal trisomy 21 risk
      LP410748-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Likelihood
LP185777-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Plas.cfDNA
LP185795-4
- System Core
  Plas.cfDNA
  LP185795-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Dosage of chromosome specific cf DNA
LP172871-8

Basic Attributes

Class: MOLPATH.TRISOMY
Type: Laboratory
First Released: Version 2.44
Last Updated: Version 2.73 (MIN)
Change Reason: The system of 'Ser/Plas.maternal^fetus' was changed to 'Plas.cfDNA' (cfDNA from plasma, which includes both maternal and fetal DNA) to more precisely identify what is being measured.; Added "Fetal" to Component to clarify that the result is about the fetus.
Order vs. Observation: Both
Common Test Rank Get Info: 9446

Member of these Panels

LOINC	Long Common Name
73967-2	Noninvasive prenatal fetal aneuploidy panel - Plasma cell-free DNA

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Trizomie 21 riziko u plodu:Pravděpodobnost:Časový bod:DNA volná cirkulující (cfDNA):Kvantitativní:Dávkování chromozomálně specifické cfDNA
el-GR	Greek (Greece)	Κίνδυνος εμβρυϊκής τρισωμίας 21:Πιθανότητα:Pt:Πλάσμα.cfDNA:Qn:Δοσολογία ειδικού χρωμοσωμικού cf DNA Synonyms: MOLPATH MOLPATH.TRISOMY Pt Qn Δοσολογία ειδικού χρωμοσωμικού cf DNA Κίνδυνος εμβρυϊκής τρισωμίας 21 Κίνδυνος τρισωμίας 21 Πιθανότητα Πλάσμα Πλάσμα.cfDNA Τρισωμία 21
es-ES	Spanish (Spain)	Riesgo de trisomía 21 fetal:Probabilidad:Punto temporal:ADN en plasma libre de células:Qn:Dosificación de ADN ccf de cromosoma específico Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Riesgo de trisomía 21 fetal:Probabilidad:Punto temporal:ADN libre de células plasmáticas:Cuantitativo:Dosis de cfDNA cromosómico específico
fr-FR	French (France)	Risque de trisomie 21 foetale:Probabilité:Ponctuel:Plasma avec ADN libre circulant:Numérique:Dosage d'ADN libre circulant spécifiques aux chromosomes
it-IT	Italian (Italy)	Trisomia 21, rischio:Probabilità:Pt:Plasma.DNA libero circolante:Qn:Dosaggio di DNA libero fetale circolante cromosoma specifico Synonyms: DNA libero circolante nel plasma Dosaggio di DNA libero fetale circolante cromosoma Patologia molecolare Plasma Punto nel tempo (episodio) Rischio di trisomia 21 Trisomia cromosoma genetica
pl-PL	Polish (Poland)	Ryzyko trisomii 21 u płodu:prawdopodobieństwo:punkt w czasie:osocze.cfDNA:ilościowy:dawkowanie swoistego dla chromosomu pozakomórkowego DNA Synonyms: Ryzyko trisomii chromosomu 21 Ryzyko trisomii chromosomu 21 u płodu wolnokrążące DNA w osoczu
pt-BR	Portuguese (Brazil)	Trissomia 21 risco:Achado:Pt:Soro/Plas maternal^feto:Qn:Dosagem de cromossomo específico ccf DNA
zh-CN	Chinese (China)	胎儿三体型 21 风险:似然性:时间点:血浆.cfDNA:定量型:染色体特异性 cfDNA 剂量测定 Synonyms: 21 三体型综合征（唐氏综合征、Down 氏综合征、Down 综合征、21 三体性、21 号染色体三体型、21 号染色体三体性） 21 三体型综合征风险（危险性、风险性、危险）;21 三体型风险;21 三体性综合征风险;21 三体性风险;21 三体综合征风险;21 三体综合症风险;21 号染色体三体型风险;21 号染色体三体性风险;Down 氏综合征风险;Down 综合征风险;DS;T21 风险;Ts 21 风险;三体性 21 风险;唐氏综合征风险;染色体 21 三体型风险;染色体 21 三体性风险三体型三体细胞三染色体性三染色体细胞分子病理学;分子病理学试验分子病理学试验类.三体性（三体型）可用数量表示的;定量性;数值型;数量型;连续数值型标尺可能性;似然;可能时刻;随机;随意;瞬间染色体特异性 cf DNA 剂量测定;染色体特异性游离循环 DNA 剂量测定;染色体特异性循环游离 DNA 剂量测定;Cell Free DNA 特异特异性的特异的胎儿 21 三体型综合征风险（危险性、风险性、危险）;胎儿 21 三体型风险;胎儿 21 三体性综合征风险;胎儿 21 三体性风险;胎儿 21 三体综合征风险;胎儿 21 三体综合症风险;胎儿 21 号染色体三体型风险;胎儿 21 号染色体三体性风险;胎儿 Down 氏综合征风险;胎儿 Down 综合征风险;胎儿 DS;胎儿 T21 风险;胎儿 Ts 21 风险;胎儿三体性 21 风险;胎儿唐氏综合征风险;胎儿染色体 21 三体型风险;胎儿染色体 21 三体性风险血浆循环 cfDNA;血浆循环 DNA;循环游离核酸;血浆游离 DNA;血浆无细胞 DNA;Free circulating/Cell-free DNA;Free circulating DNA

Example Units

Unit	Source
{risk}	Example UCUM Units

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.