LOINC
Version 2.67

73982-1Carbapenem resistance blaNDM gene [Presence] by Molecular methodActive

Term Description

Detection of bla(NDM) genotypes by PCR-based assays in isolates positive for gram-negative bacilli. Test is performed to determine resistance to carbapenems due to NDM (New Dehli metallo-β-lactamase) enzyme production.
Source: Regenstrief LOINC

Part Description

LP173523-4   Bacterial carbapenem resistance blaNDM gene
New Delhi Metallo-beta-lactamase (NDM) is an enzyme that makes bacteria resistant to a broad range of beta-lactam antibiotics, including those in the carbapenem family. NDM-1 presents as the most dominant type. The NDM gene encodes beta-lactamase enzymes called carbapenemases. The most common bacteria that make the NDM enzyme are Gram-negative such as Escherichia coli and Klebsiella pneumoniae, but the gene for NDM can spread from one strain of bacteria to another by horizontal gene transfer. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, NDM beta lactamases

Fully-Specified Name

Component
Bacterial carbapenem resistance blaNDM gene
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Molgen

Additional Names

Short Name
blaNDM Islt/Spm Ql
Display Name
Carbapenem resistance blaNDM gene Molgen Ql (Islt/Spec)

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.46
Last Updated
Version 2.66
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Corrected Component from "Bacterial carbapenemase resistance" to "Bacterial carbapenem resistance" (because the bacteria are resistant to carbapenem antibiotics by virtue of producing carbapenemase) and removed parentheses around and within the gene name according to recommended nomenclature [PMID: 25249841]; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
93698-9 Gram negative bacterial resistance panel by Molecular genetics method
93407-5 Gram negative blood culture panel by NAA with probe detection in Positive blood culture
92958-8 Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with non-probe detection

Language Variants Get Info

zh-CNChinese (CHINA)
细菌碳青霉烯类耐药 blaNDM 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
nl-NLDutch (NETHERLANDS)
bacteriële carbapenemresistentie blaNDM-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
fr-FRFrench (FRANCE)
Résistance bactérienne aux carbapénèmases blaNDM gène:Présence/Seuil:Ponctuel:Isolat:Qualitatif:PCR amplification de cible
de-ATGerman (AUSTRIA)
Carbapenem Resistenz Gen (blaNDM) qualitativ
it-ITItalian (ITALY)
Resistenza batterica ai carbapenemici, gene blaNDM:PrThr:Pt:Isolato/Campione:Ord:Molgen
pt-BRPortuguese (BRAZIL)
es-ESSpanish (SPAIN)
Resistencia bacteriana de carbapenemasas gen (bla (NDM)):PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=73982-1