74263-5

Dabigatran [Mass/volume] in Serum or Plasma by LC/MS/MS

Active

Term Description

Total dabigatran (i.e. the sum of diabigatran and its pharmacologically active glucuronides) is measured after complete alkaline cleavage of the glucuronide conjugates present in the samples by liquid chromatography/mass spectrometry (LC/MS-MS) methods. Use of liquid LC/MS-MS provides highly accurate measurement of dabigatran concentrations without the variable interferences associated with traditional clot-based and chromogenic assays. Studies performed using the LC/MS-MS method indicate that the assay is not sensitive to the presence of lupus anticoagulants or heparin administration nor to Factor VIII deficiency or the multiple factor deficiency associated with coumadin treatment.
Source: LOINC partner 1

Part Description

LP135651-0 Dabigatran
Dabigatran (marketed as Pradaxa in Australia, Europe and USA, Pradax in Canada, and Prazaxa in Japan) is an anticoagulant from the class of the direct thrombin inhibitors. It is being studied for various clinical indications and in some cases it offers an alternative to warfarin as the preferred orally administered anticoagulant ("blood thinner") since it does not require frequent blood tests for international normalized ratio (INR) monitoring while offering similar results in terms of efficacy. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name: Dabigatran:MCnc:Pt:Ser/Plas:Qn:LC/MS/MS
Long Common Name: Dabigatran [Mass/volume] in Serum or Plasma by LC/MS/MS
Short Name: Dabigatran SerPl LC/MS/MS-mCnc
Display Name: Dabigatran LC/MS/MS [Mass/Vol]
Consumer Name Alpha Get Info: Dabigatran, Blood

Part Model Get Info

Component
Dabigatran
LP135651-0
- Analyte
  Dabigatran
  LP135651-0
  - Component Numerator
    Dabigatran
    LP135651-0
    - Component Numerator Core
      Dabigatran
      LP135651-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
LC/MS/MS
LP95062-3

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.46
Last Updated: Version 2.46 (MIN)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG27575-6	Dabigatran\|MCnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Dabigatran:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:Kapalinová chromatografie s tandemovou hmotnostní spektrometrií (LC/MS/MS)
el-GR	Greek (Greece)	Δαμπιγκατράνη:MCnc:Pt:Ορός/Πλάσμα:Qn:LC/MS/MS Synonyms: DRUG/TOX LC/MS/MS MCnc Pt Qn Δαμπιγκατράνη Ορός Ορός/Πλάσμα Πλάσμα
es-ES	Spanish (Spain)	Dabigatran:Concentración de masa:Punto temporal:Suero o Plasma:Qn:LC/MS/MS Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Dabigatrán:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:LC / MS / MS
fr-CA	French (Canada)	Dabigatran:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:LC/MS/MS
fr-FR	French (France)	Dabigatran:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:LC/MS/MS
it-IT	Italian (Italy)	Dabigatran:MCnc:Pt:Siero/Plasma:Qn:LC/MS/MS Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	dabigatran:massa/volume:moment:serum of plasma:kwantitatief:LC/MS/MS
pl-PL	Polish (Poland)	Dabigatran:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy:chromatografia cieczowa z tandemową spektrometrią mas (LC-MS/MS)
tr-TR	Turkish (Turkey)	Dabigatran:KütlKons:Zmlı:Ser/Plaz:Kant:LC/MS/MS
zh-CN	Chinese (China)	达比加群:质量浓度:时间点:血清/血浆:定量型:LC/MS/MS Synonyms: Tandem Mass Spectrometry;MS/MS;串联质谱分析;串联质谱法;mass spectrometer;MS;质谱法;质谱分析;liquid chromatography;LC;液相色谱分析;Liquid Chromatography-Tandem Mass Spectrometry;liquid chromatography-MS/MS;LC-MS/MS;液相色谱分析-串联质谱分析法;液相色谱-串联质谱检测方法;液相色谱质谱联用技术;串联质谱快速分析可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆达比加群酯;dabigatran etexilate;Pradaxa;抗凝药物;抗凝血剂;凝血酶抵制药

Example Units

Unit	Source
ng/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.