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Term Description

The count of spots (0 to >20) in a patient's T cells that represent IFN-γ released in response to the presence of M. tuberculosis early secretory antigenic target-6 (ESAT-6) antigens. The spot count provides a measurement of the abundance of Mycobacterium tuberculosis sensitive effector T cells in the peripheral blood. This term is based on, but not limited in use to, Oxford Immunotec's T-SPOT.TB assay, used to diagnose M. tuberculosis. T-SPOT.TB assay uses enzyme-linked immunospot (ELISPOT) methodology to enumerate M. tuberculosis-sensitized T cells by capturing interferon-gamma (IFN-y) in the vicinity of T cells in the patient's whole blood. In the T-SPOT.TB assay, the test result is positive if [ESAT-6 (Panel A) - negative control spots] and/or [CFP10 (Panel B) - negative control spots] is greater than or equal to 8 spots. The test result is negative if both [Panel A - negative control] and/or [Panel B - negative control] is less than or equal to 4 spots.

Part Description

LP173642-2   Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count
ESAT-6, the 6 kDa early secretory antigenic target of Mycobacterium tuberculosis, is a secretory protein and potent T cell antigen. It is used in tuberculosis diagnosis by whole blood interferon γ tests, e.g. QuantiFERON-TB Gold and T-SPOT.TB, in conjunction with CFP-10 and TB7.7 (QuantiFERON-TB Gold). ESAT-6 has been shown to directly bind to the TLR2 receptor, inhibiting downstream signal transduction. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, ESAT-6

LOINC Names Get Info

Fully-Specified Name
Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count:Num:Pt:Bld:Qn:
Long Common Name
Mycobacterium tuberculosis stimulated gamma interferon ESAT-6 Ag spot count [#] in Blood
Short Name
M TB IFN-g.ESAT-6 Ag Bld
Display Name
M. tuberculosis stim IFN-g ESAT-6 Ag spot count (Bld) [#]
Consumer Name Alpha Get Info
Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count, Blood

Part Model Get Info

  • Component
    Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count
    LP173642-2
    • Analyte
      Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count
      LP173642-2
      • Component Numerator
        Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count
        LP173642-2
        • Component Numerator Core
          Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count
          LP173642-2
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Num
    LP6841-3
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.46
Last Updated
Version 2.64 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
74281-7Mycobacterium tuberculosis stimulated gamma interferon and spot count panel - Blood

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Interferon gama po stimulaci Mycobacterium tuberculosis ESAT-6 Ag počet skvrn:Počet:Časový bod:Krev:Kvantitativní:
el-GRGreek (Greece)Διεγερμένη από Mycobacterium tuberculosis (Μυκοβακτηρίδιο της φυματίωσης) γ-ιντερφερόνη.μέτρηση κηλίδων αντιγόνου ESAT-6:Αρ.:Pt:Αίμα:Qn:
Synonyms: MICRO Mycobacterium tuberculosis (Μυκοβακτηρίδιο της φυματίωσης) Pt Qn Αίμα Αρ. Διεγερμένη από Mycobacterium tuberculosis (Μυκοβακτηρίδιο της φυματίωσης) γ-ιντερφερόνη Διεγερμένη από Mycobacterium tuberculosis (Μυκοβακτηρίδιο της φυματίωσης) γ-ιντερφερόνη.μέτρηση κηλίδων αντιγόνου ESAT-6 Ιντερφερόνη
es-ESSpanish (Spain)Mycobacterium tuberculosis estimulado con interferón gamma antígeno ESAT-6 recuento de manchas:Número (recuento):Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Interferón gamma estimulado por Mycobacterium tuberculosis.ESAT-6 Ag spot count:Número (recuento):Punto temporal:Sangre:Cuantitativo:
fr-FRFrench (France)Interféron gamma stimulé par mycobacterium tuberculosis antigène ESAT-6 spots comptés:Nombre:Ponctuel:Sang:Numérique:
it-ITItalian (Italy)Interferone gamma stimolato da mycobacterium tuberculosis.antigeni ESAT6 numero di spot:Num:Pt:Sangue:Qn:
Synonyms: Gamma interferone stimolato da Mycobacterium tuber Interferone gamma stimolato da microbatterio della Micobatterio della tubercolosi Microbiologia Numero (conta) Punto nel tempo (episodio) Sangue
nl-NLDutch (Netherlands)Mycobacterium tuberculosis-gestimuleerde gamma-interferon ESAT-6-Ag spot count:aantal:moment:bloed:kwantitatief:
pl-PLPolish (Poland)Stymulowany przez Mycobacterium tuberculosis interferon gamma.Liczba spotów Ag ESAT-6:liczba:punkt w czasie:krew:ilościowy:
Synonyms: IFN-gamma stymulowany Mycobacterium tuberculosis Prątek gruźlicy Stymulowany przez Mycobacterium tuberculosis interferon gamma.Liczba spotów Ag ESAT-6
ru-RURussian (Russian Federation)Mycobacterium tuberculosis стимулированный гамма интерферон.ESAT-6 Аг пятно количество панель:Кол:ТчкВрм:Кр:Колич:
Synonyms: Количественный Количество Кровь Точка во времени;Момент
tr-TRTurkish (Turkey)Mycobacterium tuberculosis uyarılmış gamma interferon.ESAT-6 Ag spot sayım:Say:Zmlı:Kan:Kant:
zh-CNChinese (China)结核分枝杆菌刺激型 gamma 干扰素.ESAT-6 抗原斑点计数:数量(计数):时间点:全血:定量型:
Synonyms: AFB IFN 个数;数量;数量或计数（非负整数）;计数 分支杆菌 分支杆菌属 分枝杆菌属 劳瘵 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 抗酸 抗酸杆菌 抗酸杆菌（Acid fast bacillus，AFB） 抗酸菌 时刻;随机;随意;瞬间 痨 痨病 结核 结核;肺结核;痨;痨病;TB 结核分支杆菌;结核杆菌;结核菌 结核分枝杆菌刺激型 gamma 干扰素（γ干扰素、IFN-γ） 结核分枝杆菌刺激型 gamma 干扰素（γ干扰素、IFN-γ）.ESAT-6 抗原斑点（斑、点）计数 结核病 肺结核 血;血液

Example Units

UnitSource
{#}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74278-3