74631-3
Glycosaminoglycans/Creatinine [Ratio] in 24 hour Urine
Active
Part Descriptions
LP15624-7 Glycosaminoglycans
Glycosaminoglycans (GAGs) or mucopolysaccharides are long unbranched polysaccharides consisting of a repeating disaccharide unit. This unit consists of an N-acetyl-hexosamine and a hexose or hexuronic acid, either or both of which may be sulfated. Members of the glycosaminoglycan family vary in the type of hexosamine, hexose or hexuronic acid unit they contain (e.g. glucuronic acid, iduronic acid, galactose, galactosamine, glucosamine). They also vary in the geometry of the glycosidic linkage. This family of carbohydrates is essential or important for the life of vertebrates and an assortment of lower animals. GAGs form an important component of connective tissues. GAG chains may be covalently linked to a protein to form proteoglycans.
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Source: Wikipedia, Glycosaminoglycans (Wikipedia)
LP15624-7 Glycosaminoglycans
Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine.
Source: National Library of Medicine, MeSH 2006
LP15624-7 Glycosaminoglycans
The presence of glycosaminoglycans (GAGs) in urine is indicative of a mucopolysaccharidoses (MPSs) disease or sometimes bone, connective tissue, thyroid, or urinary disease or an oligosaccharidoses. The MPSs are characterized by any enzyme deficiency inolved in the degradation of a GAG molecule such as heparan sulfate, keratan sulfate, or chondroitin sulfate. GAGs then accumuilate in lysozomes causing disease which can present variably and involve multiple systems.
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Glycosaminoglycans/Creatinine
- Property
- Ratio
- Time
- 24H
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- GAG/Creat 24h Ur-Rto
- Display Name
- Glycosaminoglycans/Creatinine (24H U) [Ratio]
- Consumer Name Alpha Get Info
- Glycosaminoglycans/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.48
- Last Updated
- Version 2.48
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG36383-4 | Glycosaminoglycans/Creatinine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Glicosaminoglicanos/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Glucosaminoglicanos / Creatinina: |
| et-EE | Estonian (Estonia) | Glükoosaminoglükaanid/kreatiniin: Synonyms: Kvantitatiivne Uriin |
| fr-CA | French (Canada) | Glycosaminoglycanes/Créatinine: |
| fr-FR | French (France) | Glycosaminoglycanes/créatinine: |
| fr-BE | French (Belgium) | Glycosaminoglycanes/Créatinine: |
| it-IT | Italian (Italy) | Glicosaminoglicani/Creatinina: Synonyms: 24 Ore Chimica |
| nl-NL | Dutch (Netherlands) | glycosaminoglycanen/creatinine: Synonyms: 24U kreatinine |
| pt-BR | Portuguese (Brazil) | Glicosaminoglicanos/Creatinina: |
| ru-RU | Russian (Russian Federation) | Гликозаминогликаны/Креатинин: Synonyms: Количественный Коэффициент; |
| tr-TR | Turkish (Turkey) | Glikozaminoglicanlar/Kreatinin: |
| zh-CN | Chinese (China) | 粘多糖/肌酐: Synonyms: 1天; |
Example Units
| Unit | Source |
|---|---|
| mg/mmol{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright