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Term Description

Monoclonal Protein Peak 3 Identification in Urine by Immunofixation (IFE). Immunofixation is performed on the urine specimen to identify the immunoglobulin heavy chain and/or light chain present in the peaks.

Part Descriptions

LP182311-3   Monoclonal band 3 observed
A monoclonal band (M-spike, monoclonal protein isotype) is often found in patients with monoclonal gammopathies. Following protein electrophoresis, immunofixation is used to identify the immunoglobulin heavy chain and/or light chain. Monoclonal peaks greater than 3 g/dL and IgG or IgA are seen in patients with Multiple Myeloma (MM). A monoclonal peak greater than 3 g/dL and IgM is seen in patients with macroglobulinemia. An alternate methodology for identifying the monoclonal protein isotype is MALDI-TOF, in which known information regarding the unique mass of each isotype is used to determine and quantify the isotype present in the patient sample based on the mass spectra generated from the sample. Source: Regenstrief LOINC

LP6336-4   Immunofixation
Plasma or concentrated urine is deposited on a gel. With an electrical current the proteins are sorted in function of their size, after which antigens for each targeted type of immunoglobulin are deposited on the gel. Thus more or less narrow bands appear on the gel, marking the location of the various immunoglobulines.
Immunofixation tends to replace protein electrophoresis because:

• it is faster (results within three hours);
• it is somewhat more sensitive. Immunofixation may reveal an immunoglobulin missed out by protein electrophoresis, especially at low concentrations (less than 1 gram/litre);
• it can be partially automated and can be used in more laboratories;
• it is more easily read and interpreted.

Immunofixation is however only sensitive to immunoglobulins and is more expensive than protein electrophoresis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Immunofixation

LOINC Names Get Info

Fully-Specified Name
Monoclonal band 3 observed:Prid:Pt:Urine:Nom:Immunofixation
Long Common Name
Monoclonal band 3 observed [Identifier] in Urine by Immunofixation
Short Name
Monoclon Band 3 Obs Ur IFE
Display Name
Monoclonal band 3 observed Immunofixation Nom (U)
Consumer Name Alpha Get Info
Monoclonal band 3 observed, Urine

Part Model Get Info

  • Component
    Monoclonal band 3 observed
    LP182311-3
    • Analyte
      Monoclonal band 3 observed
      LP182311-3
      • Component Numerator
        Monoclonal band 3 observed
        LP182311-3
        • Component Numerator Core
          Monoclonal band 3 observed
          LP182311-3
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Prid
    LP6850-4
  • Time
    Pt
    LP6960-1
  • System
    Urine
    LP7681-2
    • System Core
      Urine
      LP7681-2
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Immunofixation
    LP6336-4

Example Answer List: LL2432-4

Source: Regenstrief LOINC
AnswerCodeScoreAnswer ID
KappaLA19741-0
LambdaLA19742-8

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.48 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Monoklonální pruh 3 pozorován:Přítomnost nebo identita:Časový bod:Moč:Nominální:Imunofixace
el-GRGreek (Greece)Μονοκλωνική ζώνη 3 που παρακολουθείται:Prid:Pt:Ούρα:Nom:Ανοσοκαθήλωση
Synonyms: CHEM Nom Prid Pt Ανοσοκαθήλωση Ζώνη 3 Μονοκλωνική ζώνη 3 που παρακολουθείται Ούρα
es-ESSpanish (Spain)Banda monoclonal 3 observada:Presencia o identidad:Punto temporal:Orina:Nom:Inmunofijación
es-MXSpanish (Mexico)Banda monoclonal 3 observada:Presencia o identidad:Punto temporal:Orina:Nominal:Inmunofijación
fr-FRFrench (France)Bandes monoclonales 3 observées:Identification:Ponctuel:Urine:Résultat nominal:Immunofixation
it-ITItalian (Italy)Banda monoclonale 3 osservata:Prid:Pt:Urine:Nom:Immunofissazione
Synonyms: Chimica Presenza o Identità Punto nel tempo (episodio)
nl-NLDutch (Netherlands)monoclonale band 3 waargenomen:identificator:moment:urine:nominaal:immunofixatie
pt-BRPortuguese (Brazil)Banda 3 monoclonal observada:Ident:Pt:Urina:Nom:Imunofixação
ru-RURussian (Russian Federation)Моноклональная полоса 3 наблюдённая:ПрИд:ТчкВрм:Моча:Ном:Иммунофиксация
Synonyms: Номинальный;Именной Присутствие или Идентификация Точка во времени;Момент
tr-TRTurkish (Turkey)Monoklonal band 3 gözlenen:MevcKimlik:Zmlı:İdrar:Snf:İmmünfiksasyon
zh-CNChinese (China)已观察到的单克隆区带 3:存在与否或特征标识:时间点:尿液:名义型:免疫固定电泳分析法
Synonyms: Ⅲ IFE;Ifix;免疫固定法;免疫固定电泳（Immunofixation electrophoresis，IFE）;免疫固定电泳法 III 三 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 区带 单克隆区带3观察情况;单克隆条带3观察情况;已观察的单克隆条带 3;已观察的单克隆区带 3 叁 存在;存在与否;特征标识;身份;身份标识 尿;小便;下泉 带 带3;anion exchanger AE1;阴离子交换蛋白 AE1;AE1 anion exchanger;AE1 阴离子交换蛋白;band 3 protein 带状 带状核 时刻;随机;随意;瞬间 杆 杆状核

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74638-8